Lineage for Species: Human (Homo sapiens)

  1. Root: SCOP 1.71
  2. 570216Class c: Alpha and beta proteins (a/b) [51349] (134 folds)
  3. 594893Fold c.111: Activating enzymes of the ubiquitin-like proteins [69571] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 32145678; strands 6 and 8 are antiparallel to the rest
  4. 594894Superfamily c.111.1: Activating enzymes of the ubiquitin-like proteins [69572] (2 families) (S)
    transfer adenylyl group to the C-terminal carboxyl group of the ubiquitin and MoaD/ThiS-related proteins
    the ATP nucleotide-binding site is similar to that of the NAD-binding Rossmann-folds
  5. 594901Family c.111.1.2: Ubiquitin activating enzymes (UBA) [89763] (2 proteins)
    the common fold is elaborated with additional (sub)domains
  6. 594902Protein Amyloid beta precursor protein-binding protein 1, APPBP1 [89766] (1 species)
    a subunit of the heterodimeric E1 enzyme for NEDD8; contains a large insertion (residues 170-487) that can be divided into 3 units similar to the UBA3 insertion
  7. 594903Species Human (Homo sapiens) [TaxId:9606] [89767] (4 PDB entries)

PDB entries in Species: Human (Homo sapiens):

  1. Domain(s) for 1ngv:
    1. 594904Domain d1ngva_: 1ngv A: [85698]
      Other proteins in same PDB: d1ngvb_, d1ngvd_
    2. 594905Domain d1ngvc_: 1ngv C: [85700]
      Other proteins in same PDB: d1ngvb_, d1ngvd_
      complexed with zn
  2. Domain(s) for 1r4m:
    1. 594908Domain d1r4ma_: 1r4m A: [96999]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
    2. 594909Domain d1r4mc_: 1r4m C: [97001]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
    3. 594910Domain d1r4me_: 1r4m E: [97003]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
    4. 594911Domain d1r4mg_: 1r4m G: [97005]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn; mutant
  3. Domain(s) for 1r4n:
    1. 594912Domain d1r4na_: 1r4n A: [97011]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
    2. 594913Domain d1r4nc_: 1r4n C: [97013]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
    3. 594914Domain d1r4ne_: 1r4n E: [97015]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
    4. 594915Domain d1r4ng_: 1r4n G: [97017]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn; mutant
  4. Domain(s) for 1tt5:
    1. 594906Domain d1tt5a_: 1tt5 A: [107291]
      Other proteins in same PDB: d1tt5b_, d1tt5d_
    2. 594907Domain d1tt5c_: 1tt5 C: [107293]
      Other proteins in same PDB: d1tt5b_, d1tt5d_
      complexed with zn

More info for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 Amyloid beta precursor protein-binding protein 1, APPBP1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 Amyloid beta precursor protein-binding protein 1, APPBP1: