Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2921020Fold c.111: Activating enzymes of the ubiquitin-like proteins [69571] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 32145678; strands 6 and 8 are antiparallel to the rest
  4. 2921021Superfamily c.111.1: Activating enzymes of the ubiquitin-like proteins [69572] (3 families) (S)
    transfer adenylyl group to the C-terminal carboxyl group of the ubiquitin and MoaD/ThiS-related proteins
    the ATP nucleotide-binding site is similar to that of the NAD-binding Rossmann-folds
  5. 2921028Family c.111.1.2: Ubiquitin activating enzymes (UBA) [89763] (3 proteins)
    the common fold is elaborated with additional (sub)domains
  6. 2921029Protein Amyloid beta precursor protein-binding protein 1, APPBP1 [89766] (1 species)
    a subunit of the heterodimeric E1 enzyme for NEDD8; contains a large insertion (residues 170-487) that can be divided into 3 units similar to the UBA3 insertion
  7. 2921030Species Human (Homo sapiens) [TaxId:9606] [89767] (10 PDB entries)
    Uniprot Q13564

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1ngv:
    1. 2921031Domain d1ngva_: 1ngv A: [302766]
      Other proteins in same PDB: d1ngvb_, d1ngvd_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    2. 2921032Domain d1ngvc_: 1ngv C: [302768]
      Other proteins in same PDB: d1ngvb_, d1ngvd_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
  2. Domain(s) for 1r4m:
    1. 2921048Domain d1r4ma_: 1r4m A: [96999]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    2. 2921049Domain d1r4mc_: 1r4m C: [97001]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    3. 2921050Domain d1r4me_: 1r4m E: [97003]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    4. 2921051Domain d1r4mg_: 1r4m G: [97005]
      Other proteins in same PDB: d1r4mb_, d1r4md_, d1r4mf_, d1r4mh_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
  3. Domain(s) for 1r4n:
    1. 2921056Domain d1r4na_: 1r4n A: [97011]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
      has additional subdomain(s) that are not in the common domain
    2. 2921057Domain d1r4nc_: 1r4n C: [97013]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
      has additional subdomain(s) that are not in the common domain
    3. 2921058Domain d1r4ne_: 1r4n E: [97015]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
      has additional subdomain(s) that are not in the common domain
    4. 2921059Domain d1r4ng_: 1r4n G: [97017]
      Other proteins in same PDB: d1r4nb_, d1r4nd_, d1r4nf_, d1r4nh_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
      has additional subdomain(s) that are not in the common domain
  4. Domain(s) for 1tt5:
    1. 2921035Domain d1tt5a_: 1tt5 A: [107291]
      Other proteins in same PDB: d1tt5b1, d1tt5b2, d1tt5d_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    2. 2921036Domain d1tt5c_: 1tt5 C: [107293]
      Other proteins in same PDB: d1tt5b1, d1tt5b2, d1tt5d_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
  5. Domain(s) for 1yov:
    1. 2921033Domain d1yova_: 1yov A: [123785]
      Other proteins in same PDB: d1yovb_, d1yovd_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    2. 2921034Domain d1yovc_: 1yov C: [123787]
      Other proteins in same PDB: d1yovb_, d1yovd_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
  6. Domain(s) for 2nvu:
  7. Domain(s) for 3dbh:
    1. 2921037Domain d3dbha_: 3dbh A: [157468]
      Other proteins in same PDB: d3dbhb1, d3dbhb2, d3dbhd1, d3dbhd2, d3dbhf1, d3dbhf2, d3dbhh1, d3dbhh2, d3dbhi2, d3dbhi3, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    2. 2921038Domain d3dbhc_: 3dbh C: [157469]
      Other proteins in same PDB: d3dbhb1, d3dbhb2, d3dbhd1, d3dbhd2, d3dbhf1, d3dbhf2, d3dbhh1, d3dbhh2, d3dbhi2, d3dbhi3, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    3. 2921039Domain d3dbhe_: 3dbh E: [157470]
      Other proteins in same PDB: d3dbhb1, d3dbhb2, d3dbhd1, d3dbhd2, d3dbhf1, d3dbhf2, d3dbhh1, d3dbhh2, d3dbhi2, d3dbhi3, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    4. 2921040Domain d3dbhg_: 3dbh G: [157471]
      Other proteins in same PDB: d3dbhb1, d3dbhb2, d3dbhd1, d3dbhd2, d3dbhf1, d3dbhf2, d3dbhh1, d3dbhh2, d3dbhi2, d3dbhi3, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
  8. Domain(s) for 3dbl:
    1. 2921041Domain d3dbla_: 3dbl A: [157473]
      Other proteins in same PDB: d3dblb2, d3dblb3, d3dbld2, d3dbld3, d3dblf2, d3dblf3, d3dblh2, d3dblh3, d3dbli2, d3dbli3, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    2. 2921042Domain d3dblc_: 3dbl C: [157475]
      Other proteins in same PDB: d3dblb2, d3dblb3, d3dbld2, d3dbld3, d3dblf2, d3dblf3, d3dblh2, d3dblh3, d3dbli2, d3dbli3, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    3. 2921043Domain d3dble_: 3dbl E: [157477]
      Other proteins in same PDB: d3dblb2, d3dblb3, d3dbld2, d3dbld3, d3dblf2, d3dblf3, d3dblh2, d3dblh3, d3dbli2, d3dbli3, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    4. 2921044Domain d3dblg_: 3dbl G: [157479]
      Other proteins in same PDB: d3dblb2, d3dblb3, d3dbld2, d3dbld3, d3dblf2, d3dblf3, d3dblh2, d3dblh3, d3dbli2, d3dbli3, d3dblj_, d3dblk_, d3dbll_
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
  9. Domain(s) for 3dbr:
    1. 2921052Domain d3dbra_: 3dbr A: [157482]
      Other proteins in same PDB: d3dbrb1, d3dbrb2, d3dbrd1, d3dbrd2, d3dbrf1, d3dbrf2, d3dbrh1, d3dbrh2, d3dbri1, d3dbri2, d3dbrj1, d3dbrj2, d3dbrk1, d3dbrk2, d3dbrl1, d3dbrl2
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    2. 2921053Domain d3dbrc_: 3dbr C: [157483]
      Other proteins in same PDB: d3dbrb1, d3dbrb2, d3dbrd1, d3dbrd2, d3dbrf1, d3dbrf2, d3dbrh1, d3dbrh2, d3dbri1, d3dbri2, d3dbrj1, d3dbrj2, d3dbrk1, d3dbrk2, d3dbrl1, d3dbrl2
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    3. 2921054Domain d3dbre_: 3dbr E: [157484]
      Other proteins in same PDB: d3dbrb1, d3dbrb2, d3dbrd1, d3dbrd2, d3dbrf1, d3dbrf2, d3dbrh1, d3dbrh2, d3dbri1, d3dbri2, d3dbrj1, d3dbrj2, d3dbrk1, d3dbrk2, d3dbrl1, d3dbrl2
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
    4. 2921055Domain d3dbrg_: 3dbr G: [157485]
      Other proteins in same PDB: d3dbrb1, d3dbrb2, d3dbrd1, d3dbrd2, d3dbrf1, d3dbrf2, d3dbrh1, d3dbrh2, d3dbri1, d3dbri2, d3dbrj1, d3dbrj2, d3dbrk1, d3dbrk2, d3dbrl1, d3dbrl2
      automated match to d1tt5a_
      complexed with zn
      has additional subdomain(s) that are not in the common domain
  10. Domain(s) for 3gzn:
    1. 2921046Domain d3gzna_: 3gzn A: [246396]
      Other proteins in same PDB: d3gznb_, d3gznd_, d3gzni1, d3gzni2, d3gznj1, d3gznj2
      automated match to d1tt5a_
      complexed with b39, zn
      has additional subdomain(s) that are not in the common domain
    2. 2921047Domain d3gznc_: 3gzn C: [246398]
      Other proteins in same PDB: d3gznb_, d3gznd_, d3gzni1, d3gzni2, d3gznj1, d3gznj2
      automated match to d1tt5a_
      complexed with b39, zn
      has additional subdomain(s) that are not in the common domain

More info for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 Amyloid beta precursor protein-binding protein 1, APPBP1

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 Amyloid beta precursor protein-binding protein 1, APPBP1: