Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.03
  2. 1336837Class c: Alpha and beta proteins (a/b) [51349] (147 folds)
  3. 1394913Fold c.111: Activating enzymes of the ubiquitin-like proteins [69571] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 32145678; strands 6 and 8 are antiparallel to the rest
  4. 1394914Superfamily c.111.1: Activating enzymes of the ubiquitin-like proteins [69572] (3 families) (S)
    transfer adenylyl group to the C-terminal carboxyl group of the ubiquitin and MoaD/ThiS-related proteins
    the ATP nucleotide-binding site is similar to that of the NAD-binding Rossmann-folds
  5. 1394921Family c.111.1.2: Ubiquitin activating enzymes (UBA) [89763] (2 proteins)
    the common fold is elaborated with additional (sub)domains
  6. 1394949Protein UBA3 [89764] (1 species)
    a subunit of the heterodimeric E1 enzyme for NEDD8; contains an all-alpha insert subdomain of the FF-like fold (residues 210-288) and an extra C-terminal alpha+beta subdomain (partly disordered)
  7. 1394950Species Human (Homo sapiens) [TaxId:9606] [89765] (9 PDB entries)
    Uniprot Q8TBC4 33-458

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1r4m:
    1. 1394966Domain d1r4mb_: 1r4m B: [97000]
      Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
    2. 1394967Domain d1r4md_: 1r4m D: [97002]
      Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
    3. 1394968Domain d1r4mf_: 1r4m F: [97004]
      Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
    4. 1394969Domain d1r4mh_: 1r4m H: [97006]
      Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_
      complexed with zn
  2. Domain(s) for 1r4n:
    1. 1394970Domain d1r4nb_: 1r4n B: [97012]
      Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
    2. 1394971Domain d1r4nd_: 1r4n D: [97014]
      Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
    3. 1394972Domain d1r4nf_: 1r4n F: [97016]
      Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
    4. 1394973Domain d1r4nh_: 1r4n H: [97018]
      Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_
      complexed with atp, zn
  3. Domain(s) for 1tt5:
    1. 1394955Domain d1tt5b_: 1tt5 B: [107292]
      Other proteins in same PDB: d1tt5a_, d1tt5c_
      complexed with zn
    2. 1394956Domain d1tt5d_: 1tt5 D: [107294]
      Other proteins in same PDB: d1tt5a_, d1tt5c_
      complexed with zn
  4. Domain(s) for 1y8x:
  5. Domain(s) for 1yov:
    1. 1394952Domain d1yovb_: 1yov B: [123786]
      Other proteins in same PDB: d1yova_, d1yovc_
      automated match to d1ngvb_
      complexed with zn
    2. 1394953Domain d1yovd_: 1yov D: [123788]
      Other proteins in same PDB: d1yova_, d1yovc_
      automated match to d1ngvb_
      complexed with zn
  6. Domain(s) for 2nvu:
  7. Domain(s) for 3dbh:
    1. 1394957Domain d3dbhb_: 3dbh B: [161640]
      Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1r4mb_
      complexed with zn
    2. 1394958Domain d3dbhd_: 3dbh D: [161641]
      Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1r4mb_
      complexed with zn
    3. 1394959Domain d3dbhf_: 3dbh F: [161642]
      Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1r4mb_
      complexed with zn
    4. 1394960Domain d3dbhh_: 3dbh H: [161643]
      Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_
      automated match to d1r4mb_
      complexed with zn
  8. Domain(s) for 3dbl:
    1. 1394961Domain d3dblb_: 3dbl B: [157474]
      Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1r4mb_
      complexed with zn
    2. 1394962Domain d3dbld_: 3dbl D: [157476]
      Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1r4mb_
      complexed with zn
    3. 1394963Domain d3dblf_: 3dbl F: [157478]
      Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1r4mb_
      complexed with zn
    4. 1394964Domain d3dblh_: 3dbl H: [157480]
      Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_
      automated match to d1r4mb_
      complexed with zn
  9. Domain(s) for 3fn1:

More info for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 UBA3

Timeline for Species Human (Homo sapiens) [TaxId:9606] from c.111.1.2 UBA3: