Class c: Alpha and beta proteins (a/b) [51349] (147 folds) |
Fold c.111: Activating enzymes of the ubiquitin-like proteins [69571] (1 superfamily) 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 32145678; strands 6 and 8 are antiparallel to the rest |
Superfamily c.111.1: Activating enzymes of the ubiquitin-like proteins [69572] (3 families) transfer adenylyl group to the C-terminal carboxyl group of the ubiquitin and MoaD/ThiS-related proteins the ATP nucleotide-binding site is similar to that of the NAD-binding Rossmann-folds |
Family c.111.1.2: Ubiquitin activating enzymes (UBA) [89763] (2 proteins) the common fold is elaborated with additional (sub)domains |
Protein UBA3 [89764] (1 species) a subunit of the heterodimeric E1 enzyme for NEDD8; contains an all-alpha insert subdomain of the FF-like fold (residues 210-288) and an extra C-terminal alpha+beta subdomain (partly disordered) |
Human (Homo sapiens) [TaxId:9606] [89765] (8 PDB entries) Uniprot Q8TBC4 33-458 |
Domain d1r4mb_: 1r4m B: [97000] Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_ complexed with zn |
Domain d1r4md_: 1r4m D: [97002] Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_ complexed with zn |
Domain d1r4mf_: 1r4m F: [97004] Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_ complexed with zn |
Domain d1r4mh_: 1r4m H: [97006] Other proteins in same PDB: d1r4ma_, d1r4mc_, d1r4me_, d1r4mg_, d1r4mi_, d1r4mj_, d1r4mk_, d1r4ml_ complexed with zn |
Domain d1r4nb_: 1r4n B: [97012] Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_ complexed with atp, zn |
Domain d1r4nd_: 1r4n D: [97014] Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_ complexed with atp, zn |
Domain d1r4nf_: 1r4n F: [97016] Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_ complexed with atp, zn |
Domain d1r4nh_: 1r4n H: [97018] Other proteins in same PDB: d1r4na_, d1r4nc_, d1r4ne_, d1r4ng_, d1r4ni_, d1r4nj_, d1r4nk_, d1r4nl_ complexed with atp, zn |
Domain d1tt5b_: 1tt5 B: [107292] Other proteins in same PDB: d1tt5a_, d1tt5c_ complexed with zn |
Domain d1tt5d_: 1tt5 D: [107294] Other proteins in same PDB: d1tt5a_, d1tt5c_ complexed with zn |
Domain d1y8xb1: 1y8x B:349-440 [144607] Other proteins in same PDB: d1y8xa1 C-terminal, E2 binding domain only; (this domain belongs to Pfam PF08825) |
Domain d1yovb_: 1yov B: [123786] Other proteins in same PDB: d1yova_, d1yovc_ automated match to d1ngvb_ complexed with zn |
Domain d1yovd_: 1yov D: [123788] Other proteins in same PDB: d1yova_, d1yovc_ automated match to d1ngvb_ complexed with zn |
Domain d3dbhb_: 3dbh B: [161640] Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_ automated match to d1r4mb_ complexed with zn |
Domain d3dbhd_: 3dbh D: [161641] Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_ automated match to d1r4mb_ complexed with zn |
Domain d3dbhf_: 3dbh F: [161642] Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_ automated match to d1r4mb_ complexed with zn |
Domain d3dbhh_: 3dbh H: [161643] Other proteins in same PDB: d3dbha_, d3dbhc_, d3dbhe_, d3dbhg_, d3dbhi_, d3dbhj_, d3dbhk_, d3dbhl_ automated match to d1r4mb_ complexed with zn |
Domain d3dblb_: 3dbl B: [157474] Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_ automated match to d1r4mb_ complexed with zn |
Domain d3dbld_: 3dbl D: [157476] Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_ automated match to d1r4mb_ complexed with zn |
Domain d3dblf_: 3dbl F: [157478] Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_ automated match to d1r4mb_ complexed with zn |
Domain d3dblh_: 3dbl H: [157480] Other proteins in same PDB: d3dbla_, d3dblc_, d3dble_, d3dblg_, d3dbli_, d3dblj_, d3dblk_, d3dbll_ automated match to d1r4mb_ complexed with zn |
Timeline for Protein UBA3 from c.111.1.2: Ubiquitin activating enzymes (UBA):