SCOPe 2.08: Family c.52.1.20: XPF/Rad1/Mus81 nuclease

Lineage for Family c.52.1.20: XPF/Rad1/Mus81 nuclease

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (37 families)

5. Family c.52.1.20: XPF/Rad1/Mus81 nuclease [89716] (3 proteins)

Proteins:

1. DNA excision repair protein ERCC-1 [142445] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142446] (3 PDB entries)
     Uniprot P07992 99-227

2. Putative ATP-dependent RNA helicase Hef, nuclease domain [89717] (1 species)

   • Species Pyrococcus furiosus [TaxId:2261] [89718] (4 PDB entries)

3. XPF endonuclease [142447] (1 species)

   • Species Aeropyrum pernix [TaxId:56636] [142448] (2 PDB entries)
     Uniprot Q9YC15 16-148

More info for Family c.52.1.20: XPF/Rad1/Mus81 nuclease

Timeline for Family c.52.1.20: XPF/Rad1/Mus81 nuclease:

• Family c.52.1.20: XPF/Rad1/Mus81 nuclease first appeared in SCOP 1.65
  
• Family c.52.1.20: XPF/Rad1/Mus81 nuclease appears in SCOPe 2.07