Lineage for Species: Escherichia coli

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 312976Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 312977Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 313136Family c.36.1.10: TK-like PP module [88760] (2 proteins)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 313141Protein Transketolase (TK), PP module [88761] (3 species)
  7. 313157Species Escherichia coli [TaxId:562] [89656] (1 PDB entry)

PDB entry in Species: Escherichia coli:

More info for Species Escherichia coli [TaxId:562] from c.36.1.10 Transketolase (TK), PP module

Timeline for Species Escherichia coli [TaxId:562] from c.36.1.10 Transketolase (TK), PP module: