Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.116: alpha/beta knot [75216] (1 superfamily) core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot |
Superfamily c.116.1: alpha/beta knot [75217] (9 families) known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily all known members have dimeric structures |
Family c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (2 proteins) fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain |
Protein tRNA(m1G37)-methyltransferase TrmD [89630] (3 species) |
Aquifex aeolicus [TaxId:63363] [102278] (1 PDB entry) |
Domain d1oy5a_: 1oy5 A: [93718] a TrmD topoisomer that lacks the knot; misfolded inactive structure? |
Domain d1oy5b_: 1oy5 B: [93719] a TrmD topoisomer that lacks the knot; misfolded inactive structure? |
Domain d1oy5c_: 1oy5 C: [93720] a TrmD topoisomer that lacks the knot; misfolded inactive structure? |
Escherichia coli [TaxId:562] [110499] (1 PDB entry) Uniprot P07020 |
Domain d1p9pa_: 1p9p A: [104092] complexed with sah |
Haemophilus influenzae [TaxId:727] [89631] (4 PDB entries) |
Domain d1uaja1: 1uaj A:1-246 [88381] Other proteins in same PDB: d1uaja2 |
Domain d1uaka1: 1uak A:1-246 [88382] Other proteins in same PDB: d1uaka2, d1uaka3 complexed with sam |
Domain d1uala1: 1ual A:1-246 [88383] Other proteins in same PDB: d1uala2, d1uala3 complexed with sah |
Domain d1uama1: 1uam A:1-246 [88384] Other proteins in same PDB: d1uama2, d1uama3 complexed with po4, sah |
Timeline for Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD: