SCOPe 2.08: Protein: tRNA(m1G37)-methyltransferase TrmD

Root: SCOPe 2.08
Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
Fold c.116: alpha/beta knot [75216] (1 superfamily)
core: 3 layers: a/b/a, parallel beta-sheet of 5 strands, order 21435; contains a deep trefoil knot
Superfamily c.116.1: alpha/beta knot [75217] (9 families)
known or predicted SAM-dependent methytransferases including the SPOUT 'sequence' superfamily
all known members have dimeric structures
Family c.116.1.4: tRNA(m1G37)-methyltransferase TrmD [89629] (2 proteins)
fold and dimerisation mode are similar to those of the YbeA-like family; contains additional C-terminal all-alpha subdomain
Protein tRNA(m1G37)-methyltransferase TrmD [89630] (3 species)

Aquifex aeolicus [TaxId:63363] [102278] (1 PDB entry)
- Domains for 1oy5:
  1. Domain d1oy5a_: 1oy5 A: [93718]
    a TrmD topoisomer that lacks the knot; misfolded inactive structure?
  2. Domain d1oy5b_: 1oy5 B: [93719]
    a TrmD topoisomer that lacks the knot; misfolded inactive structure?
  3. Domain d1oy5c_: 1oy5 C: [93720]
    a TrmD topoisomer that lacks the knot; misfolded inactive structure?
Escherichia coli [TaxId:562] [110499] (1 PDB entry)
Uniprot P07020
- Domain for 1p9p:
  - Domain d1p9pa_: 1p9p A: [104092]
    complexed with sah
Haemophilus influenzae [TaxId:727] [89631] (4 PDB entries)
1. Domain for 1uaj:
  - Domain d1uaja1: 1uaj A:1-246 [88381]
    Other proteins in same PDB: d1uaja2
2. Domain for 1uak:
  - Domain d1uaka1: 1uak A:1-246 [88382]
    Other proteins in same PDB: d1uaka2, d1uaka3
    complexed with sam
3. Domain for 1ual:
  - Domain d1uala1: 1ual A:1-246 [88383]
    Other proteins in same PDB: d1uala2, d1uala3
    complexed with sah
4. Domain for 1uam:
  - Domain d1uama1: 1uam A:1-246 [88384]
    Other proteins in same PDB: d1uama2, d1uama3
    complexed with po4, sah

Timeline for Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD:

Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD first appeared in SCOP 1.65
Protein tRNA(m1G37)-methyltransferase TrmD from c.116.1.4: tRNA(m1G37)-methyltransferase TrmD appears in SCOPe 2.07