SCOP 1.73: Protein: Glucosylceramidase, catalytic domain

Lineage for Protein: Glucosylceramidase, catalytic domain

Root: SCOP 1.73
Class c: Alpha and beta proteins (a/b) [51349] (141 folds)

Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
the first seven superfamilies have similar phosphate-binding sites

Superfamily c.1.8: (Trans)glycosidases [51445] (14 families)
Family c.1.8.3: beta-glycanases [51487] (24 proteins)
consist of a number of sequence families
Protein Glucosylceramidase, catalytic domain [89473] (1 species)
acid-beta-glucosidase; glycosyl hydrolase family 30; contains additional beta-domain similar to one found in alpha amylases

Species:

Human (Homo sapiens) [TaxId:9606] [89474] (7 PDB entries)
1. Domains for 1ogs:
  1. Domain d1ogsa2: 1ogs A:78-431 [86998]
    Other proteins in same PDB: d1ogsa1, d1ogsb1
  2. Domain d1ogsb2: 1ogs B:78-431 [87000]
    Other proteins in same PDB: d1ogsa1, d1ogsb1
    complexed with nag, ndg, so4
2. Domains for 1y7v:
  1. Domain d1y7va2: 1y7v A:78-431 [122726]
    Other proteins in same PDB: d1y7va1, d1y7vb1
    automatically matched to d1ogsa2
    complexed with ins, nag, so4; mutant
  2. Domain d1y7vb2: 1y7v B:78-431 [122728]
    Other proteins in same PDB: d1y7va1, d1y7vb1
    automatically matched to d1ogsa2
    complexed with ins, nag, so4; mutant
3. Domains for 2f61:
  1. Domain d2f61a2: 2f61 A:78-431 [133018]
    Other proteins in same PDB: d2f61a1, d2f61b1
    automatically matched to d1ogsa2
    complexed with nag, ndg, so4
  2. Domain d2f61b2: 2f61 B:78-431 [133020]
    Other proteins in same PDB: d2f61a1, d2f61b1
    automatically matched to d1ogsa2
    complexed with nag, ndg, so4
4. Domains for 2j25:
  1. Domain d2j25a2: 2j25 A:78-431 [137956]
    Other proteins in same PDB: d2j25a1, d2j25b1
    automatically matched to d1ogsa2
    complexed with bma, man, nag, so4
  2. Domain d2j25b2: 2j25 B:78-431 [137958]
    Other proteins in same PDB: d2j25a1, d2j25b1
    automatically matched to d1ogsa2
    complexed with bma, man, nag, so4
5. Domains for 2nsx:
  1. Domain d2nsxa2: 2nsx A:78-431 [138553]
    Other proteins in same PDB: d2nsxa1, d2nsxb1, d2nsxc1, d2nsxd1
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
  2. Domain d2nsxb2: 2nsx B:78-431 [138555]
    Other proteins in same PDB: d2nsxa1, d2nsxb1, d2nsxc1, d2nsxd1
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
  3. Domain d2nsxc2: 2nsx C:78-431 [138557]
    Other proteins in same PDB: d2nsxa1, d2nsxb1, d2nsxc1, d2nsxd1
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
  4. Domain d2nsxd2: 2nsx D:78-431 [138559]
    Other proteins in same PDB: d2nsxa1, d2nsxb1, d2nsxc1, d2nsxd1
    automatically matched to d1ogsa2
    complexed with gol, ifm, nag, ndg, so4
6. Domains for 2nt0:
  1. Domain d2nt0a2: 2nt0 A:78-431 [138562]
    Other proteins in same PDB: d2nt0a1, d2nt0b1, d2nt0c1, d2nt0d1
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
  2. Domain d2nt0b2: 2nt0 B:78-431 [138564]
    Other proteins in same PDB: d2nt0a1, d2nt0b1, d2nt0c1, d2nt0d1
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
  3. Domain d2nt0c2: 2nt0 C:78-431 [138566]
    Other proteins in same PDB: d2nt0a1, d2nt0b1, d2nt0c1, d2nt0d1
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
  4. Domain d2nt0d2: 2nt0 D:78-431 [138568]
    Other proteins in same PDB: d2nt0a1, d2nt0b1, d2nt0c1, d2nt0d1
    automatically matched to d1ogsa2
    complexed with gol, nag, so4
7. Domains for 2nt1:
  1. Domain d2nt1a2: 2nt1 A:78-431 [138570]
    Other proteins in same PDB: d2nt1a1, d2nt1b1, d2nt1c1, d2nt1d1
    automatically matched to d1ogsa2
    complexed with nag, po4
  2. Domain d2nt1b2: 2nt1 B:78-431 [138572]
    Other proteins in same PDB: d2nt1a1, d2nt1b1, d2nt1c1, d2nt1d1
    automatically matched to d1ogsa2
    complexed with nag, po4
  3. Domain d2nt1c2: 2nt1 C:78-431 [138574]
    Other proteins in same PDB: d2nt1a1, d2nt1b1, d2nt1c1, d2nt1d1
    automatically matched to d1ogsa2
    complexed with nag, po4
  4. Domain d2nt1d2: 2nt1 D:78-431 [138576]
    Other proteins in same PDB: d2nt1a1, d2nt1b1, d2nt1c1, d2nt1d1
    automatically matched to d1ogsa2
    complexed with nag, po4

More info for Protein Glucosylceramidase, catalytic domain from c.1.8.3: beta-glycanases

Timeline for Protein Glucosylceramidase, catalytic domain from c.1.8.3: beta-glycanases:

Protein Glucosylceramidase, catalytic domain from c.1.8.3: beta-glycanases first appeared in SCOP 1.65
Protein Glucosylceramidase, catalytic domain from c.1.8.3: beta-glycanases appears in SCOP 1.71
Protein Glucosylceramidase, catalytic domain from c.1.8.3: beta-glycanases appears in SCOP 1.75
Protein Glucosylceramidase, catalytic domain from c.1.8.3: beta-glycanases appears in the current release, SCOPe 2.08