SCOP 1.69: Superfamily b.129.1: AbrB/MazE/MraZ-like

Lineage for Superfamily b.129.1: AbrB/MazE/MraZ-like

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.129: AbrB/MazE/MraZ-like [89446] (1 superfamily)
   pseudobarrel; capped on both ends by alpha-helices

4. Superfamily b.129.1: AbrB/MazE/MraZ-like [89447] (3 families)
   members of this superfamily are known or predicted to have DNA-binding function

Families:

1. b.129.1.1: Kis/PemI addiction antidote [89448] (1 protein)
   forms intertwined homodimer

2. b.129.1.2: Hypothetical protein MraZ [102020] (1 protein)
   duplication: contains two interlocking repeats of similar sequence arranged as subunits in the MazE homodimer

3. b.129.1.3: Transcription-state regulator AbrB, the N-terminal DNA recognition domain [54743] (1 protein)
   dimeric fold similar to MazE; the DNA-binding site is similar to the conserved surface site of MraZ

More info for Superfamily b.129.1: AbrB/MazE/MraZ-like

Timeline for Superfamily b.129.1: AbrB/MazE/MraZ-like:

• Superfamily b.129.1: AbrB/MazE/MraZ-like first appeared in SCOP 1.65, called Superfamily b.129.1: Kis/PemI addiction antidote
  
• Superfamily b.129.1: AbrB/MazE/MraZ-like was called Superfamily b.129.1: MazE/MraZ-like in SCOP 1.67
  
• Superfamily b.129.1: AbrB/MazE/MraZ-like appears in SCOP 1.71
  
• Superfamily b.129.1: AbrB/MazE/MraZ-like appears in the current release, SCOPe 2.08