SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Fold b.129: Double-split beta-barrel

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2077397Fold b.129: Double-split beta-barrel [89446] (2 superfamilies)
    pseudobarrel; capped on both ends by alpha-helices

Superfamilies:

  1. 2077398b.129.1: AbrB/MazE/MraZ-like [89447] (3 families) (S)
    members of this superfamily are known or predicted to have DNA-binding function
  2. 2077453b.129.2: AF2212/PG0164-like [141694] (2 families) (S)
    six-stranded barrel, topologically similar to the Reductase/isomerase/elongation factor domain fold (50412)

More info for Fold b.129: Double-split beta-barrel

Timeline for Fold b.129: Double-split beta-barrel: