SCOPe 2.06: Protein: Synaptosomal-associated protein SNAP-25

Lineage for Protein: Synaptosomal-associated protein SNAP-25

Root: SCOPe 2.06
Class h: Coiled coil proteins [57942] (7 folds)
Fold h.1: Parallel coiled-coil [57943] (38 superfamilies)
this is not a true fold; includes oligomers of shorter identical helices
Superfamily h.1.15: SNARE fusion complex [58038] (2 families)
tetrameric parallel coiled coil
Family h.1.15.1: SNARE fusion complex [58039] (12 proteins)
Protein Synaptosomal-associated protein SNAP-25 [88915] (3 species)
provides up to two different helical regions to synaptic fusion complexes

Species:

Human (Homo sapiens) [TaxId:9606] [88917] (5 PDB entries)
Uniprot P60880 146-204 # identical sequence to rat species

Domains for 1kil:
1. Domain d1kilc_: 1kil C: [72520]
  Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
  complex with syntaxin, synaptobrevin and complexin fragments
  complexed with mg
2. Domain d1kild_: 1kil D: [72521]
  Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
  complex with syntaxin, synaptobrevin and complexin fragments
  complexed with mg
Domain for 1xtg:
- Domain d1xtgb_: 1xtg B: [116021]
  Other proteins in same PDB: d1xtga1, d1xtga2
  complexed the catalytic domain of the botulinum neurotoxin
  complexed with cl, zn
Domains for 2n1t:
1. Domain d2n1tc_: 2n1t C: [273433]
  Other proteins in same PDB: d2n1ta_, d2n1tb_, d2n1te1, d2n1te2
  automated match to d1n7sc_
2. Domain d2n1td_: 2n1t D: [273436]
  Other proteins in same PDB: d2n1ta_, d2n1tb_, d2n1te1, d2n1te2
  automated match to d1sfcd_
Domains for 3rk2:
1. Domain d3rk2c1: 3rk2 C:7-82 [249133]
  Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
  automated match to d1n7sc_
  complexed with ca
2. Domain d3rk2d1: 3rk2 D:141-203 [249134]
  Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
  automated match to d1kild_
  complexed with ca
3. Domain d3rk2g1: 3rk2 G:7-82 [249136]
  Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
  automated match to d1n7sc_
  complexed with ca
4. Domain d3rk2h1: 3rk2 H:141-203 [249137]
  Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
  automated match to d1kild_
  complexed with ca

Domains for 5low:

Domain d5lowe_: 5low E: [335651]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1kild_
complexed with ca, gol

2266453

Domain d5lowg1: 5low G:141-199 [335649]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1kild_
complexed with ca, gol

Domain d5lowl_: 5low L: [335787]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1kild_
complexed with ca, gol

2266455

Domain d5lown1: 5low N:141-198 [335903]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1kild_
complexed with ca, gol

Longfin inshore squid (Loligo pealei) [TaxId:6621] [88918] (1 PDB entry)
- Domains for 1l4a:
  1. Domain d1l4ac_: 1l4a C: [73561]
    Other proteins in same PDB: d1l4aa_, d1l4ab1, d1l4ab2, d1l4ae_
    complex with syntaxin, synaptobrevin and synaphin fragments
  2. Domain d1l4ad_: 1l4a D: [73562]
    Other proteins in same PDB: d1l4aa_, d1l4ab1, d1l4ab2, d1l4ae_
    complex with syntaxin, synaptobrevin and synaphin fragments

Norway rat (Rattus norvegicus) [TaxId:10116] [88916] (7 PDB entries)
Uniprot P13795 7-83; 142-204 # identical sequences to human species

Domains for 1jth:
1. Domain d1jtha_: 1jth A: [67270]
  Other proteins in same PDB: d1jthb_, d1jthd_
  complex with syntaxin fragments
2. Domain d1jthc_: 1jth C: [67272]
  Other proteins in same PDB: d1jthb_, d1jthd_
  complex with syntaxin fragments
Domains for 1n7s:
1. Domain d1n7sc1: 1n7s C:7-83 [80273]
  Other proteins in same PDB: d1n7sa1, d1n7sa2, d1n7sb1, d1n7sb2, d1n7sc2, d1n7sd2
  complex with synaptobrevin and syntaxin fragments
  complexed with ca, mpd
2. Domain d1n7sd1: 1n7s D:141-204 [80274]
  Other proteins in same PDB: d1n7sa1, d1n7sa2, d1n7sb1, d1n7sb2, d1n7sc2, d1n7sd2
  complex with synaptobrevin and syntaxin fragments
  complexed with ca, mpd
Domains for 1sfc:
1. Domain d1sfcc_: 1sfc C: [45645]
  Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
  complex with synaptobrevin and syntaxin fragments
  complexed with mpd, sr
2. Domain d1sfcd_: 1sfc D: [45646]
  Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
  complex with synaptobrevin and syntaxin fragments
  complexed with mpd, sr
3. Domain d1sfcg_: 1sfc G: [45649]
  Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
  complex with synaptobrevin and syntaxin fragments
  complexed with mpd, sr
4. Domain d1sfch_: 1sfc H: [45650]
  Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
  complex with synaptobrevin and syntaxin fragments
  complexed with mpd, sr
5. Domain d1sfck_: 1sfc K: [45653]
  Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
  complex with synaptobrevin and syntaxin fragments
  complexed with mpd, sr
6. Domain d1sfcl_: 1sfc L: [45654]
  Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
  complex with synaptobrevin and syntaxin fragments
  complexed with mpd, sr
Domains for 1urq:
1. Domain d1urqc_: 1urq C: [107996]
  Other proteins in same PDB: d1urqa_, d1urqb_, d1urqd2
2. Domain d1urqd1: 1urq D:141-199 [107997]
  Other proteins in same PDB: d1urqa_, d1urqb_, d1urqd2

Domains for 5low:

2266478

Domain d5lowd1: 5low D:7-72 [335642]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1sfck_
complexed with ca, gol

Domain d5lowf_: 5low F: [335680]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1sfck_
complexed with ca, gol

2266480

Domain d5lowk1: 5low K:7-74 [335907]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1sfck_
complexed with ca, gol

Domain d5lowm_: 5low M: [335895]
Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
automated match to d1sfck_
complexed with ca, gol

Domains for 5w5c:
1. Domain d5w5cc_: 5w5c C: [338406]
  Other proteins in same PDB: d5w5cb_, d5w5cf1, d5w5cf2
  automated match to d1sfck_
  complexed with gol, mg
2. Domain d5w5cd_: 5w5c D: [338389]
  Other proteins in same PDB: d5w5cb_, d5w5cf1, d5w5cf2
  automated match to d1sfcl_
  complexed with gol, mg
Domains for 5w5d:
1. Domain d5w5dc_: 5w5d C: [338366]
  Other proteins in same PDB: d5w5db_, d5w5df_
  automated match to d1sfck_
  complexed with mg
2. Domain d5w5dd_: 5w5d D: [338343]
  Other proteins in same PDB: d5w5db_, d5w5df_
  automated match to d1sfcl_
  complexed with mg

More info for Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex

Timeline for Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex:

Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex first appeared in SCOP 1.65, called Protein Synaptosomal-assosiated protein SNAP-25 from h.1.15.1: SNARE fusion complex
Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex appears in SCOPe 2.05
Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex appears in SCOPe 2.07
Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex appears in the current release, SCOPe 2.08