Lineage for Protein: Synaptosomal-associated protein SNAP-25

  1. Root: SCOPe 2.07
  2. 2590057Class h: Coiled coil proteins [57942] (7 folds)
  3. 2590058Fold h.1: Parallel coiled-coil [57943] (41 superfamilies)
    this is not a true fold; includes oligomers of shorter identical helices
  4. 2591003Superfamily h.1.15: SNARE fusion complex [58038] (2 families) (S)
    tetrameric parallel coiled coil
  5. 2591004Family h.1.15.1: SNARE fusion complex [58039] (12 proteins)
  6. 2591034Protein Synaptosomal-associated protein SNAP-25 [88915] (3 species)
    provides up to two different helical regions to synaptic fusion complexes

Species:

  1. 2591035Human (Homo sapiens) [TaxId:9606] [88917] (4 PDB entries)
    Uniprot P60880 146-204 # identical sequence to rat species
    1. Domains for 1kil:
      1. 2591041Domain d1kilc_: 1kil C: [72520]
        Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
        complex with syntaxin, synaptobrevin and complexin fragments
        complexed with mg
      2. 2591042Domain d1kild_: 1kil D: [72521]
        Other proteins in same PDB: d1kila_, d1kilb_, d1kile_
        complex with syntaxin, synaptobrevin and complexin fragments
        complexed with mg
    2. Domain for 1xtg:
      • 2591040Domain d1xtgb_: 1xtg B: [116021]
        Other proteins in same PDB: d1xtga1, d1xtga2
        complexed the catalytic domain of the botulinum neurotoxin
        complexed with cl, zn
    3. Domains for 2n1t:
      1. 2591043Domain d2n1tc_: 2n1t C: [273433]
        Other proteins in same PDB: d2n1ta_, d2n1tb_, d2n1te1, d2n1te2
        automated match to d1n7sc_
      2. 2591044Domain d2n1td_: 2n1t D: [273436]
        Other proteins in same PDB: d2n1ta_, d2n1tb_, d2n1te1, d2n1te2
        automated match to d1sfcd_
    4. Domains for 3rk2:
      1. 2591036Domain d3rk2c1: 3rk2 C:7-82 [249133]
        Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
        automated match to d1n7sc_
        complexed with ca
      2. 2591037Domain d3rk2d1: 3rk2 D:141-203 [249134]
        Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
        automated match to d1kild_
        complexed with ca
      3. 2591038Domain d3rk2g1: 3rk2 G:7-82 [249136]
        Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
        automated match to d1n7sc_
        complexed with ca
      4. 2591039Domain d3rk2h1: 3rk2 H:141-203 [249137]
        Other proteins in same PDB: d3rk2b1, d3rk2b2, d3rk2c2, d3rk2d2, d3rk2f1, d3rk2f2, d3rk2g2, d3rk2h2
        automated match to d1kild_
        complexed with ca
  2. 2591045Longfin inshore squid (Loligo pealei) [TaxId:6621] [88918] (1 PDB entry)
  3. 2591048Norway rat (Rattus norvegicus) [TaxId:10116] [88916] (7 PDB entries)
    Uniprot P13795 7-83; 142-204 # identical sequences to human species
    1. Domains for 1jth:
      1. 2591055Domain d1jtha_: 1jth A: [67270]
        Other proteins in same PDB: d1jthb_, d1jthd_
        complex with syntaxin fragments
      2. 2591056Domain d1jthc_: 1jth C: [67272]
        Other proteins in same PDB: d1jthb_, d1jthd_
        complex with syntaxin fragments
    2. Domains for 1n7s:
      1. 2591049Domain d1n7sc1: 1n7s C:7-83 [80273]
        Other proteins in same PDB: d1n7sa1, d1n7sa2, d1n7sb1, d1n7sb2, d1n7sc2, d1n7sd2
        complex with synaptobrevin and syntaxin fragments
        complexed with ca, mpd
      2. 2591050Domain d1n7sd1: 1n7s D:141-204 [80274]
        Other proteins in same PDB: d1n7sa1, d1n7sa2, d1n7sb1, d1n7sb2, d1n7sc2, d1n7sd2
        complex with synaptobrevin and syntaxin fragments
        complexed with ca, mpd
    3. Domains for 1sfc:
      1. 2591059Domain d1sfcc_: 1sfc C: [45645]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      2. 2591060Domain d1sfcd_: 1sfc D: [45646]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      3. 2591061Domain d1sfcg_: 1sfc G: [45649]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      4. 2591062Domain d1sfch_: 1sfc H: [45650]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      5. 2591063Domain d1sfck_: 1sfc K: [45653]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
      6. 2591064Domain d1sfcl_: 1sfc L: [45654]
        Other proteins in same PDB: d1sfca_, d1sfcb_, d1sfce_, d1sfcf_, d1sfci_, d1sfcj_
        complex with synaptobrevin and syntaxin fragments
        complexed with mpd, sr
    4. Domains for 1urq:
      1. 2591051Domain d1urqc_: 1urq C: [107996]
        Other proteins in same PDB: d1urqa_, d1urqb_, d1urqd2
      2. 2591052Domain d1urqd1: 1urq D:141-199 [107997]
        Other proteins in same PDB: d1urqa_, d1urqb_, d1urqd2
    5. Domains for 5low:
      1. 2591065Domain d5lowd1: 5low D:7-72 [335642]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1sfck_
        complexed with ca, gol
      2. 2591066Domain d5lowe_: 5low E: [335651]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1kild_
        complexed with ca, gol
      3. 2591067Domain d5lowf_: 5low F: [335680]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1sfck_
        complexed with ca, gol
      4. 2591068Domain d5lowg1: 5low G:141-199 [335649]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1kild_
        complexed with ca, gol
      5. 2591069Domain d5lowk1: 5low K:7-74 [335907]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1sfck_
        complexed with ca, gol
      6. 2591070Domain d5lowl_: 5low L: [335787]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1kild_
        complexed with ca, gol
      7. 2591071Domain d5lowm_: 5low M: [335895]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1sfck_
        complexed with ca, gol
      8. 2591072Domain d5lown1: 5low N:141-198 [335903]
        Other proteins in same PDB: d5lowa_, d5lowb_, d5lowc_, d5lowd2, d5lowg2, d5lowh_, d5lowi_, d5lowj_, d5lowk2, d5lown2
        automated match to d1kild_
        complexed with ca, gol
    6. Domains for 5w5c:
      1. 2591053Domain d5w5cc_: 5w5c C: [338406]
        Other proteins in same PDB: d5w5cb_, d5w5cf1, d5w5cf2
        automated match to d1sfck_
        complexed with gol, mg
      2. 2591054Domain d5w5cd_: 5w5c D: [338389]
        Other proteins in same PDB: d5w5cb_, d5w5cf1, d5w5cf2
        automated match to d1sfcl_
        complexed with gol, mg
    7. Domains for 5w5d:
      1. 2591057Domain d5w5dc_: 5w5d C: [338366]
        Other proteins in same PDB: d5w5db_, d5w5df_
        automated match to d1sfck_
        complexed with mg
      2. 2591058Domain d5w5dd_: 5w5d D: [338343]
        Other proteins in same PDB: d5w5db_, d5w5df_
        automated match to d1sfcl_
        complexed with mg

More info for Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex

Timeline for Protein Synaptosomal-associated protein SNAP-25 from h.1.15.1: SNARE fusion complex: