Lineage for Protein: Transketolase (TK), PP module

  1. Root: SCOP 1.73
  2. 681097Class c: Alpha and beta proteins (a/b) [51349] (141 folds)
  3. 694610Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 694611Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 694972Family c.36.1.10: TK-like PP module [88760] (2 proteins)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 694987Protein Transketolase (TK), PP module [88761] (4 species)

Species:

  1. 694988Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88762] (7 PDB entries)
    1. Domains for 1ay0:
      1. 695001Domain d1ay0a1: 1ay0 A:3-337 [31823]
        Other proteins in same PDB: d1ay0a2, d1ay0a3, d1ay0b2, d1ay0b3
      2. 695002Domain d1ay0b1: 1ay0 B:3-337 [31825]
        Other proteins in same PDB: d1ay0a2, d1ay0a3, d1ay0b2, d1ay0b3
        complexed with ca, tpp; mutant
    2. Domains for 1gpu:
      1. 694989Domain d1gpua1: 1gpu A:3-337 [65454]
        Other proteins in same PDB: d1gpua2, d1gpua3, d1gpub2, d1gpub3
      2. 694990Domain d1gpub1: 1gpu B:3-337 [65457]
        Other proteins in same PDB: d1gpua2, d1gpua3, d1gpub2, d1gpub3
        complexed with ca, thd
    3. Domains for 1ngs:
      1. 694995Domain d1ngsa1: 1ngs A:3-337 [31819]
        Other proteins in same PDB: d1ngsa2, d1ngsa3, d1ngsb2, d1ngsb3
      2. 694996Domain d1ngsb1: 1ngs B:3-337 [31821]
        Other proteins in same PDB: d1ngsa2, d1ngsa3, d1ngsb2, d1ngsb3
        complexed with ca, e4p, tpp
    4. Domains for 1tka:
      1. 694997Domain d1tkaa1: 1tka A:3-337 [31815]
        Other proteins in same PDB: d1tkaa2, d1tkaa3, d1tkab2, d1tkab3
      2. 694998Domain d1tkab1: 1tka B:3-337 [31817]
        Other proteins in same PDB: d1tkaa2, d1tkaa3, d1tkab2, d1tkab3
        complexed with ca, n3t
    5. Domains for 1tkb:
      1. 694991Domain d1tkba1: 1tkb A:3-337 [31807]
        Other proteins in same PDB: d1tkba2, d1tkba3, d1tkbb2, d1tkbb3
      2. 694992Domain d1tkbb1: 1tkb B:3-337 [31809]
        Other proteins in same PDB: d1tkba2, d1tkba3, d1tkbb2, d1tkbb3
        complexed with ca, n1t
    6. Domains for 1tkc:
      1. 694999Domain d1tkca1: 1tkc A:3-337 [31811]
        Other proteins in same PDB: d1tkca2, d1tkca3, d1tkcb2, d1tkcb3
      2. 695000Domain d1tkcb1: 1tkc B:3-337 [31813]
        Other proteins in same PDB: d1tkca2, d1tkca3, d1tkcb2, d1tkcb3
        complexed with ca, m6t
    7. Domains for 1trk:
      1. 694993Domain d1trka1: 1trk A:3-337 [31803]
        Other proteins in same PDB: d1trka2, d1trka3, d1trkb2, d1trkb3
      2. 694994Domain d1trkb1: 1trk B:3-337 [31805]
        Other proteins in same PDB: d1trka2, d1trka3, d1trkb2, d1trkb3
        complexed with ca, tpp
  2. 695003Escherichia coli [TaxId:562] [89656] (1 PDB entry)
  3. 695006Leishmania mexicana mexicana [TaxId:44270] [117524] (1 PDB entry)
  4. 695009Maize (Zea mays) [TaxId:4577] [88763] (1 PDB entry)

More info for Protein Transketolase (TK), PP module from c.36.1.10: TK-like PP module

Timeline for Protein Transketolase (TK), PP module from c.36.1.10: TK-like PP module: