Lineage for Protein: Branched-chain alpha-keto acid dehydrogenase, Pyr module

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 312976Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 312977Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 313058Family c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module [88741] (4 proteins)
    parent family to TK and PFOR
    heterodimeric protein related to TK; alpha-subunit is the PP module and the N-terminal domain of beta-subunit is the Pyr module
  6. 313062Protein Branched-chain alpha-keto acid dehydrogenase, Pyr module [88742] (1 species)

Species:

More info for Protein Branched-chain alpha-keto acid dehydrogenase, Pyr module from c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module

Timeline for Protein Branched-chain alpha-keto acid dehydrogenase, Pyr module from c.36.1.7: Branched-chain alpha-keto acid dehydrogenase Pyr module: