Lineage for Species: Escherichia coli

  1. Root: SCOP 1.69
  2. 473232Class c: Alpha and beta proteins (a/b) [51349] (136 folds)
  3. 483377Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 483378Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 483457Family c.36.1.6: TK-like Pyr module [88735] (2 proteins)
    different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain
  6. 483458Protein Pyruvate dehydrogenase E1 component, Pyr module [88739] (1 species)
    E1A and E1B fused together in a single-chain protein
  7. 483459Species Escherichia coli [TaxId:562] [88740] (2 PDB entries)

PDB entries in Species: Escherichia coli:

  1. Domain(s) for 1l8a:
    1. 483460Domain d1l8aa2: 1l8a A:471-700 [73678]
      Other proteins in same PDB: d1l8aa1, d1l8aa3, d1l8ab1, d1l8ab3
    2. 483461Domain d1l8ab2: 1l8a B:471-700 [73681]
      Other proteins in same PDB: d1l8aa1, d1l8aa3, d1l8ab1, d1l8ab3
  2. Domain(s) for 1rp7:
    1. 483462Domain d1rp7a1: 1rp7 A:471-700 [97702]
      Other proteins in same PDB: d1rp7a2, d1rp7a3, d1rp7b2, d1rp7b3
    2. 483463Domain d1rp7b1: 1rp7 B:471-700 [97705]
      Other proteins in same PDB: d1rp7a2, d1rp7a3, d1rp7b2, d1rp7b3

More info for Species Escherichia coli [TaxId:562] from c.36.1.6 Pyruvate dehydrogenase E1 component, Pyr module

Timeline for Species Escherichia coli [TaxId:562] from c.36.1.6 Pyruvate dehydrogenase E1 component, Pyr module: