Lineage for Species: Brewer's yeast (Saccharomyces), uvarum strain
- Root: SCOP 1.67
Class c: Alpha and beta proteins (a/b) [51349] (130 folds) 
Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) 
there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme moleculesFamily c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (7 proteins)
the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology
Protein Pyruvate decarboxylase [88725] (3 species) 
Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [88726] (1 PDB entry)
PDB entry in Species: Brewer's yeast (Saccharomyces), uvarum strain:
- Domain(s) for 1pyd:
Domain d1pyda2: 1pyd A:2-181 [31773]
Other proteins in same PDB: d1pyda1, d1pyda3, d1pydb1, d1pydb3
Domain d1pydb2: 1pyd B:2-181 [31775]
Other proteins in same PDB: d1pyda1, d1pyda3, d1pydb1, d1pydb3
complexed with mg, tdp
More info for Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.5 Pyruvate decarboxylase
Timeline for Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.5 Pyruvate decarboxylase:
- Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.5 Pyruvate decarboxylase first appeared in SCOP 1.65
- Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.5 Pyruvate decarboxylase appears in SCOP 1.69
- Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] from c.36.1.5 Pyruvate decarboxylase appears in the current release, SCOPe 2.08, called Species Brewer's yeast (Saccharomyces uvarum) [TaxId:230603] from c.36.1.5 Pyruvate decarboxylase