Lineage for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

  1. Root: SCOP 1.67
  2. 383641Class c: Alpha and beta proteins (a/b) [51349] (130 folds)
  3. 393047Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 393048Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 393049Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (7 proteins)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpha/beta domain of Rossmann-like topology

Proteins:

  1. 393050Acetohydroxyacid synthase catalytic subunit [88733] (1 species)
  2. 393056Benzoylformate decarboxylase [88731] (1 species)
  3. 393075Carboxyethylarginine synthase [102330] (1 species)
  4. 393091Catabolic acetolactate synthase [102328] (1 species)
  5. 393101Indole-3-pyruvate decarboxylase [89648] (1 species)
  6. 393107Pyruvate decarboxylase [88725] (3 species)
    1. 393108Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88727] (2 PDB entries)
    2. 393113Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [88726] (1 PDB entry)
    3. 393116Species Zymomonas mobilis [TaxId:542] [88728] (1 PDB entry)
  7. 393121Pyruvate oxidase [88729] (1 species)

More info for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

Timeline for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module: