Lineage for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 312976Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465
  4. 312977Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families) (S)
    there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
    two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules
  5. 312978Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module [88724] (5 proteins)
    the N-terminal, Pyr module is separated from the C-terminal, PP module by an alpa/beta domain of Rossmann-like topology

Proteins:

  1. 312979Acetohydroxyacid synthase catalytic subunit [88733] (1 species)
  2. 312985Benzoylformate decarboxylase [88731] (1 species)
  3. 313004Indole-3-pyruvate decarboxylase [89648] (1 species)
  4. 313010Pyruvate decarboxylase [88725] (3 species)
    1. 313011Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [88727] (2 PDB entries)
    2. 313016Species Brewer's yeast (Saccharomyces), uvarum strain [TaxId:230603] [88726] (1 PDB entry)
    3. 313019Species Zymomonas mobilis [TaxId:542] [88728] (1 PDB entry)
  5. 313024Pyruvate oxidase [88729] (1 species)

More info for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module

Timeline for Family c.36.1.5: Pyruvate oxidase and decarboxylase Pyr module: