SCOPe 2.06: Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

Lineage for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
   sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
   characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies

4. Superfamily b.121.4: Positive stranded ssRNA viruses [88633] (10 families)

5. Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) [88634] (10 proteins)
   the order of the chains N-VP0-VP3-VP1-C is as in the polyprotein; VP0 is cleaved later upon capsid assembly to VP4 and VP2
   there is a different order in the shuffled genome of insect picorna-like proteins (Cricket paralysis virus)

Proteins:

1. Aphthovirus (Foot-and-mouth disease virus) coat proteins [49659] (1 species)

   • Species FMDV (Foot-and-mouth disease virus), strain bfs, 1860 [TaxId:12110] [49660] (4 PDB entries)

2. Bovine enterovirus coat proteins [49676] (1 species)

   • Species Bovine enterovirus, VG-5-27 [TaxId:12064] [49677] (1 PDB entry)

3. Human enterovirus B coat proteins [88635] (4 species)

   1. Species Human coxsackievirus A9 [TaxId:12067] [49683] (1 PDB entry)

   2. Species Human coxsackievirus B3 [TaxId:12072] [49681] (2 PDB entries)

   3. Species Human echovirus 1 [TaxId:46633] [49685] (1 PDB entry)

   4. Species Human echovirus 11 [TaxId:12078] [74890] (3 PDB entries)

4. Insect picorna-like virus coat proteins [49654] (1 species)
   different genetic order of VP segments due to extensive genome shuffling

   • Species Cricket paralysis virus [TaxId:12136] [49655] (1 PDB entry)

5. Mengo encephalomyocarditis virus coat proteins [49678] (1 species)

   • Species Mengovirus [TaxId:12107] [49679] (2 PDB entries)

6. Poliovirus coat proteins [49666] (3 species)

   1. Species Poliovirus type 1, strain Mahoney [TaxId:12080] [49667] (12 PDB entries)

   2. Species Poliovirus type 2, strain Lansing [TaxId:12083] [49668] (1 PDB entry)

   3. Species Poliovirus type 3, strain Sabin [TaxId:12086] [49669] (7 PDB entries)

7. Rhinovirus coat proteins [49670] (5 species)

   1. Species Human rhinovirus 16, (HRV-16) [TaxId:31708] [49672] (9 PDB entries)

   2. Species Human rhinovirus 3, (HRV-3) [TaxId:44130] [49675] (1 PDB entry)

   3. Species Human rhinovirus A 1A (HRV-1A) [TaxId:12134] [49673] (4 PDB entries)

   4. Species Human rhinovirus A 2 (HRV-2) [TaxId:12130] [49674] (2 PDB entries)

   5. Species Human rhinovirus B 14 (HRV-14) [TaxId:12131] [49671] (33 PDB entries)

8. Swine vesicular disease virus coat proteins [89225] (1 species)

   • Species Swine vesicular disease virus [TaxId:12075] [89226] (2 PDB entries)

9. Theilovirus capsid proteins [49686] (1 species)

   • Species Theiler's murine encephalomyelitis virus, strain da [TaxId:12124] [49687] (2 PDB entries)

10. automated matches [190854] (15 species)
    not a true protein

    1. Species Coxsackievirus a16 (strain tainan/5079/98) [TaxId:231417] [277504] (1 PDB entry)

    2. Species Coxsackievirus a16 [TaxId:31704] [276274] (3 PDB entries)

    3. Species Coxsackievirus a24 [TaxId:12089] [260750] (4 PDB entries)

    4. Species Coxsackievirus a6 [TaxId:86107] [339711] (2 PDB entries)

    5. Species Enterovirus e [TaxId:12064] [335693] (2 PDB entries)

    6. Species Foot-and-mouth disease virus - type a [TaxId:12111] [196861] (4 PDB entries)

    7. Species Foot-and-mouth disease virus - type o [TaxId:12118] [335439] (2 PDB entries)

    8. Species Foot-and-mouth disease virus [TaxId:12110] [188180] (8 PDB entries)

    9. Species Foot-and-mouth disease virus [TaxId:12122] [255673] (1 PDB entry)

    10. Species Human coxsackievirus B3 [TaxId:12072] [194627] (1 PDB entry)

    11. Species Human echovirus 7 [TaxId:46018] [255678] (1 PDB entry)

    12. Species Human enterovirus 71 [TaxId:39054] [195913] (11 PDB entries)

    13. Species Human rhinovirus 14 [TaxId:12131] [258112] (2 PDB entries)

    14. Species Human rhinovirus 2 [TaxId:12130] [256100] (1 PDB entry)

    15. Species Saffold virus [TaxId:434309] [318368] (2 PDB entries)

More info for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

Timeline for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4):

• Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) first appeared in SCOP 1.65
  
• Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) appears in SCOPe 2.05
  
• Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) appears in SCOPe 2.07
  
• Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) appears in the current release, SCOPe 2.08