Lineage for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2075417Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
    sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
    characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies
  4. 2075626Superfamily b.121.4: Positive stranded ssRNA viruses [88633] (10 families) (S)
  5. 2075627Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) [88634] (10 protein domains)
    the order of the chains N-VP0-VP3-VP1-C is as in the polyprotein; VP0 is cleaved later upon capsid assembly to VP4 and VP2
    there is a different order in the shuffled genome of insect picorna-like proteins (Cricket paralysis virus)

Protein Domains:

  1. 2075628Aphthovirus (Foot-and-mouth disease virus) coat proteins [49659] (1 species)
  2. 2075642Bovine enterovirus coat proteins [49676] (1 species)
  3. 2075647Human enterovirus B coat proteins [88635] (4 species)
    1. 2075648Species Human coxsackievirus A9 [TaxId:12067] [49683] (1 PDB entry)
    2. 2075652Species Human coxsackievirus B3 [TaxId:12072] [49681] (2 PDB entries)
    3. 2075657Species Human echovirus 1 [TaxId:46633] [49685] (1 PDB entry)
    4. 2075661Species Human echovirus 11 [TaxId:12078] [74890] (3 PDB entries)
  4. 2075670Insect picorna-like virus coat proteins [49654] (1 species)
    different genetic order of VP segments due to extensive genome shuffling
  5. 2075675Mengo encephalomyocarditis virus coat proteins [49678] (1 species)
  6. 2075683Poliovirus coat proteins [49666] (3 species)
    1. 2075684Species Poliovirus type 1, strain Mahoney [TaxId:12080] [49667] (12 PDB entries)
    2. 2075719Species Poliovirus type 2, strain Lansing [TaxId:12083] [49668] (1 PDB entry)
    3. 2075723Species Poliovirus type 3, strain Sabin [TaxId:12086] [49669] (7 PDB entries)
  7. 2075745Rhinovirus coat proteins [49670] (5 species)
    1. 2075746Species Human rhinovirus 16, (HRV-16) [TaxId:31708] [49672] (9 PDB entries)
    2. 2075774Species Human rhinovirus 3, (HRV-3) [TaxId:44130] [49675] (1 PDB entry)
    3. 2075778Species Human rhinovirus A 1A (HRV-1A) [TaxId:12134] [49673] (4 PDB entries)
    4. 2075791Species Human rhinovirus A 2 (HRV-2) [TaxId:12130] [49674] (2 PDB entries)
    5. 2075798Species Human rhinovirus B 14 (HRV-14) [TaxId:12131] [49671] (33 PDB entries)
  8. 2075889Swine vesicular disease virus coat proteins [89225] (1 species)
  9. 2075897Theilovirus capsid proteins [49686] (1 species)
  10. 2075905automated matches [190854] (15 species)
    not a true protein
    1. 2075906Species Coxsackievirus a16 (strain tainan/5079/98) [TaxId:231417] [277504] (1 PDB entry)
    2. 2075908Species Coxsackievirus a16 [TaxId:31704] [276274] (3 PDB entries)
    3. 2075912Species Coxsackievirus a24 [TaxId:12089] [260750] (4 PDB entries)
    4. 2075921Species Foot-and-mouth disease virus - type a [TaxId:12111] [196861] (4 PDB entries)
    5. 2075930Species Foot-and-mouth disease virus [TaxId:12110] [188180] (8 PDB entries)
    6. 2075935Species Foot-and-mouth disease virus [TaxId:12122] [255673] (1 PDB entry)
    7. 2075937Species Human coxsackievirus B3 [TaxId:12072] [194627] (1 PDB entry)
    8. 2075939Species Human echovirus 7 [TaxId:46018] [255678] (1 PDB entry)
    9. 2075942Species Human enterovirus 71 [TaxId:39054] [195913] (11 PDB entries)
    10. 2075962Species Human rhinovirus 14 [TaxId:12131] [258112] (2 PDB entries)
    11. 2075965Species Human rhinovirus 2 [TaxId:12130] [256100] (1 PDB entry)
    12. 2275067Species Saffold virus [TaxId:434309] [318368] (2 PDB entries)
    13. 2292138Species Foot-and-mouth disease virus - type o [TaxId:12118] [335439] (2 PDB entries)
    14. 2292392Species Enterovirus e [TaxId:12064] [335693] (2 PDB entries)
    15. 2296410Species Coxsackievirus a6 [TaxId:86107] [339711] (2 PDB entries)

More info for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4)

Timeline for Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4):