Class b: All beta proteins [48724] (126 folds) |
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
Superfamily b.1.1: Immunoglobulin [48726] (4 families) |
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins) |
Protein Immunoglobulin heavy chain variable domain, VH [88543] (19 species) VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogeneous CDRs are listed as engineered species |
Species Human (Homo sapiens), cluster 3 [TaxId:9606] [88547] (10 PDB entries) |
Domain d1aqkh1: 1aqk H:1-123 [20193] Other proteins in same PDB: d1aqkh2, d1aqkl1, d1aqkl2 part of Fab B7-15A2 |
Domain d1deeb1: 1dee B:501-621 [20443] Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_ |
Domain d1deed1: 1dee D:1501-1621 [20445] Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_ |
Domain d1deef1: 1dee F:2501-2621 [20447] Other proteins in same PDB: d1deea1, d1deea2, d1deeb2, d1deec1, d1deec2, d1deed2, d1deee1, d1deee2, d1deef2, d1deeg_, d1deeh_ part of IgM RF 2A2 |
Domain d1dfbh1: 1dfb H:1-126 [19811] Other proteins in same PDB: d1dfbh2, d1dfbl1, d1dfbl2 part of Fab 3D6 |
Domain d1dqlh_: 1dql H: [19829] Other proteins in same PDB: d1dqll_ part of IgM Fv MEZ |
Domain d1igmh_: 1igm H: [19827] Other proteins in same PDB: d1igml_ part of IgM Fv POT |
Domain d2fb4h1: 2fb4 H:1-119 [19847] Other proteins in same PDB: d2fb4h2, d2fb4l1, d2fb4l2 part of Fab KOL |
Domain d2ig2h1: 2ig2 H:1-119 [19849] Other proteins in same PDB: d2ig2h2, d2ig2l1, d2ig2l2 part of antibody KOL; intact protein but only Fab's can be seen in the crystal structure |
Timeline for Species Human (Homo sapiens), cluster 3 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: