Lineage for Species: Human (Homo sapiens), cluster 2.2

  1. Root: SCOP 1.65
  2. 287094Class b: All beta proteins [48724] (126 folds)
  3. 287095Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 287096Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 287097Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins)
  6. 287195Protein Immunoglobulin heavy chain variable domain, VH [88543] (19 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogeneous CDRs are listed as engineered species
  7. 287253Species Human (Homo sapiens), cluster 2.2 [TaxId:9606] [88546] (1 PDB entry)

PDB entry in Species: Human (Homo sapiens), cluster 2.2:

More info for Species Human (Homo sapiens), cluster 2.2 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH

Timeline for Species Human (Homo sapiens), cluster 2.2 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: