![]() | Class b: All beta proteins [48724] (126 folds) |
![]() | Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
![]() | Superfamily b.1.1: Immunoglobulin [48726] (4 families) ![]() |
![]() | Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins) |
![]() | Protein Immunoglobulin heavy chain variable domain, VH [88543] (19 species) VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogeneous CDRs are listed as engineered species |
![]() | Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88544] (7 PDB entries) |
![]() | Domain d1hzhh1: 1hzh H:1-113 [61437] Other proteins in same PDB: d1hzhh2, d1hzhh3, d1hzhh4, d1hzhk2, d1hzhk3, d1hzhk4, d1hzhl1, d1hzhl2, d1hzhm1, d1hzhm2 |
![]() | Domain d1hzhk1: 1hzh K:1-113 [61441] Other proteins in same PDB: d1hzhh2, d1hzhh3, d1hzhh4, d1hzhk2, d1hzhk3, d1hzhk4, d1hzhl1, d1hzhl2, d1hzhm1, d1hzhm2 part of intact IgG B12 antibody complexed with fuc, gal, man, nag |
![]() | Domain d1iqdb1: 1iqd B:1-114 [62646] Other proteins in same PDB: d1iqda1, d1iqda2, d1iqdb2, d1iqdc_ part of intact IgG B12 antibody mutant |
![]() | Domain d1jv5b_: 1jv5 B: [67345] Other proteins in same PDB: d1jv5a_ part of an anti-blood group A Fv |
![]() | Domain d1vgeh1: 1vge H:1-122 [20095] Other proteins in same PDB: d1vgeh2, d1vgel1, d1vgel2 part of humanized Fab TR1.9 |
Timeline for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin heavy chain variable domain, VH: