Lineage for Species: Human (Homo sapiens), cluster 2 [TaxId: 9606]
- Root: SCOPe 2.05
Class b: All beta proteins [48724] (176 folds) 
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
sandwich; 7 strands in 2 sheets; greek-key
some members of the fold have additional strands
Superfamily b.1.1: Immunoglobulin [48726] (5 families) 
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins) 
Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline familySpecies Human (Homo sapiens), cluster 2 [TaxId:9606] [88536] (10 PDB entries)
PDB entries in Species: Human (Homo sapiens), cluster 2 [TaxId: 9606]:
- Domain(s) for 1bjm:
Domain d1bjma1: 1bjm A:1-111 [20524]
Other proteins in same PDB: d1bjma2, d1bjmb2
VL dimer of Bence-Jones protein LOC
Domain d1bjmb1: 1bjm B:1-111 [20525]
Other proteins in same PDB: d1bjma2, d1bjmb2
VL dimer of Bence-Jones protein LOC
- Domain(s) for 1nl0:
Domain d1nl0l1: 1nl0 L:1-108 [91947]
Other proteins in same PDB: d1nl0g_, d1nl0h1, d1nl0h2, d1nl0l2
part of Fab 10c12 against factor IX Gla domain
complexed with ca, so4
- Domain(s) for 1q1j:
- Domain(s) for 1rzf:
Domain d1rzfl1: 1rzf L:2-108 [98152]
Other proteins in same PDB: d1rzfh1, d1rzfh2, d1rzfl2
part of anti HIV-1 gp120-reactive Fab E51
complexed with gol, ipa
- Domain(s) for 2fb4:
Domain d2fb4l1: 2fb4 L:1-109 [19846]
Other proteins in same PDB: d2fb4h1, d2fb4h2, d2fb4l2
part of Fab KOL
- Domain(s) for 2ig2:
Domain d2ig2l1: 2ig2 L:1-109 [19848]
Other proteins in same PDB: d2ig2h1, d2ig2h2, d2ig2l2
part of antibody KOL; intact protein but only Fab's can be seen in the crystal structure
- Domain(s) for 2j6e:
- Domain(s) for 2rhe:
Domain d2rhea_: 2rhe A: [20523]
VL of Bence-Jones protein RHE
- Domain(s) for 3bjl:
Domain d3bjla1: 3bjl A:1-111 [20526]
Other proteins in same PDB: d3bjla2, d3bjlb2
VL dimer of Bence-Jones protein LOC
Domain d3bjlb1: 3bjl B:1-111 [20527]
Other proteins in same PDB: d3bjla2, d3bjlb2
VL dimer of Bence-Jones protein LOC
- Domain(s) for 4bjl:
Domain d4bjla1: 4bjl A:2-111 [20528]
Other proteins in same PDB: d4bjla2, d4bjlb2
VL dimer of Bence-Jones protein LOC
Domain d4bjlb1: 4bjl B:2-111 [20529]
Other proteins in same PDB: d4bjla2, d4bjlb2
VL dimer of Bence-Jones protein LOC
More info for Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda
Timeline for Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda:
- Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda first appeared in SCOP 1.65
- Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda appears in SCOPe 2.04
- Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda appears in SCOPe 2.06
- Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda appears in the current release, SCOPe 2.08