Lineage for Species: Human (Homo sapiens), cluster 2 [TaxId: 9606]

  1. Root: SCOPe 2.02
  2. 1103260Class b: All beta proteins [48724] (174 folds)
  3. 1103261Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1103262Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1103263Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1105202Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 1105215Species Human (Homo sapiens), cluster 2 [TaxId:9606] [88536] (10 PDB entries)

PDB entries in Species: Human (Homo sapiens), cluster 2 [TaxId: 9606]:

  1. Domain(s) for 1bjm:
    1. 1105220Domain d1bjma1: 1bjm A:1-111 [20524]
      Other proteins in same PDB: d1bjma2, d1bjmb2
      VL dimer of Bence-Jones protein LOC
    2. 1105221Domain d1bjmb1: 1bjm B:1-111 [20525]
      Other proteins in same PDB: d1bjma2, d1bjmb2
      VL dimer of Bence-Jones protein LOC
  2. Domain(s) for 1nl0:
  3. Domain(s) for 1q1j:
    1. 1105226Domain d1q1jl1: 1q1j L:1-108 [95585]
      Other proteins in same PDB: d1q1jh1, d1q1jh2, d1q1ji1, d1q1ji2, d1q1jl2, d1q1jm2
      part of anti HIV-1 Fab 447-52d
    2. 1105227Domain d1q1jm1: 1q1j M:1-108 [95587]
      Other proteins in same PDB: d1q1jh1, d1q1jh2, d1q1ji1, d1q1ji2, d1q1jl2, d1q1jm2
      part of anti HIV-1 Fab 447-52d
  4. Domain(s) for 1rzf:
  5. Domain(s) for 2fb4:
  6. Domain(s) for 2ig2:
  7. Domain(s) for 2j6e:
    1. 1105229Domain d2j6el1: 2j6e L:1-108 [145669]
      Other proteins in same PDB: d2j6ea1, d2j6ea2, d2j6eb1, d2j6eb2, d2j6eh1, d2j6eh2, d2j6ei1, d2j6ei2, d2j6el2, d2j6em2
      complexed with act, cac, cd, mpd, zn
    2. 1105230Domain d2j6em1: 2j6e M:1-108 [145671]
      Other proteins in same PDB: d2j6ea1, d2j6ea2, d2j6eb1, d2j6eb2, d2j6eh1, d2j6eh2, d2j6ei1, d2j6ei2, d2j6el2, d2j6em2
      automatically matched to 2J6E L:1-108
      complexed with act, cac, cd, mpd, zn
  8. Domain(s) for 2rhe:
  9. Domain(s) for 3bjl:
    1. 1105222Domain d3bjla1: 3bjl A:1-111 [20526]
      Other proteins in same PDB: d3bjla2, d3bjlb2
      VL dimer of Bence-Jones protein LOC
    2. 1105223Domain d3bjlb1: 3bjl B:1-111 [20527]
      Other proteins in same PDB: d3bjla2, d3bjlb2
      VL dimer of Bence-Jones protein LOC
  10. Domain(s) for 4bjl:
    1. 1105224Domain d4bjla1: 4bjl A:2-111 [20528]
      Other proteins in same PDB: d4bjla2, d4bjlb2
      VL dimer of Bence-Jones protein LOC
    2. 1105225Domain d4bjlb1: 4bjl B:2-111 [20529]
      Other proteins in same PDB: d4bjla2, d4bjlb2
      VL dimer of Bence-Jones protein LOC

More info for Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 2 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda: