Lineage for Species: Human (Homo sapiens), cluster 1 [TaxId: 9606]

  1. Root: SCOPe 2.05
  2. 1755445Class b: All beta proteins [48724] (176 folds)
  3. 1755446Fold b.1: Immunoglobulin-like beta-sandwich [48725] (31 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1755447Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1755448Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)
  6. 1757501Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (9 species)
    VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family
  7. 1757505Species Human (Homo sapiens), cluster 1 [TaxId:9606] [88535] (4 PDB entries)
    SQ NA # Bence-Jones protein JTO ! Uniprot P06317 # Ig lambda chain V-VI region SUT

PDB entries in Species: Human (Homo sapiens), cluster 1 [TaxId: 9606]:

  1. Domain(s) for 1cd0:
    1. 1757508Domain d1cd0a_: 1cd0 A: [20559]
      VL dimer of Bence-Jones protein JTO
    2. 1757509Domain d1cd0b_: 1cd0 B: [20560]
      VL dimer of Bence-Jones protein JTO
  2. Domain(s) for 1pew:
    1. 1757506Domain d1pewa_: 1pew A: [104135]
      complexed with cd; mutant
    2. 1757507Domain d1pewb_: 1pew B: [104136]
      complexed with cd; mutant
  3. Domain(s) for 1pw3:
    1. 1757510Domain d1pw3a_: 1pw3 A: [104335]
      complexed with cd
    2. 1757511Domain d1pw3b_: 1pw3 B: [104336]
      complexed with cd
  4. Domain(s) for 2cd0:
    1. 1757512Domain d2cd0a_: 2cd0 A: [20561]
      VL dimer of Bence-Jones protein WIL
    2. 1757513Domain d2cd0b_: 2cd0 B: [20562]
      VL dimer of Bence-Jones protein WIL

More info for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda

Timeline for Species Human (Homo sapiens), cluster 1 [TaxId:9606] from b.1.1.1 Immunoglobulin light chain lambda variable domain, VL-lambda: