Class b: All beta proteins [48724] (126 folds) |
Fold b.1: Immunoglobulin-like beta-sandwich [48725] (20 superfamilies) sandwich; 7 strands in 2 sheets; greek-key some members of the fold have additional strands |
Superfamily b.1.1: Immunoglobulin [48726] (4 families) |
Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (21 proteins) |
Protein Immunoglobulin light chain lambda variable domain, VL-lambda [88534] (8 species) VL-lambda domains of human antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the human genome; mouse VL-lambda domains belong to a single germline family |
Hamster (Cricetulus griseus) [TaxId:10029] [88542] (1 PDB entry) |
Domain d1nfde1: 1nfd E:2-107 [20186] Other proteins in same PDB: d1nfda1, d1nfda2, d1nfdb1, d1nfdb2, d1nfdc1, d1nfdc2, d1nfdd1, d1nfdd2, d1nfde2, d1nfdf1, d1nfdf2, d1nfdg2, d1nfdh1, d1nfdh2 |
Domain d1nfdg1: 1nfd G:2-107 [20188] Other proteins in same PDB: d1nfda1, d1nfda2, d1nfdb1, d1nfdb2, d1nfdc1, d1nfdc2, d1nfdd1, d1nfdd2, d1nfde2, d1nfdf1, d1nfdf2, d1nfdg2, d1nfdh1, d1nfdh2 part of Fab H57 complexed with nag |
Human (Homo sapiens), cluster 1 [TaxId:9606] [88535] (2 PDB entries) |
Domain d1cd0a_: 1cd0 A: [20559] |
Domain d1cd0b_: 1cd0 B: [20560] VL dimer of Bence-Jones protein JTO |
Domain d2cd0a_: 2cd0 A: [20561] |
Domain d2cd0b_: 2cd0 B: [20562] VL dimer of Bence-Jones protein WIL |
Human (Homo sapiens), cluster 2 [TaxId:9606] [88536] (6 PDB entries) |
Domain d1bjma1: 1bjm A:1-111 [20524] Other proteins in same PDB: d1bjma2, d1bjmb2 |
Domain d1bjmb1: 1bjm B:1-111 [20525] Other proteins in same PDB: d1bjma2, d1bjmb2 VL dimer of Bence-Jones protein LOC |
Domain d2fb4l1: 2fb4 L:1-109 [19846] Other proteins in same PDB: d2fb4h1, d2fb4h2, d2fb4l2 part of Fab KOL |
Domain d2ig2l1: 2ig2 L:1-109 [19848] Other proteins in same PDB: d2ig2h1, d2ig2h2, d2ig2l2 part of antibody KOL; intact protein but only Fab's can be seen in the crystal structure |
Domain d2rhe__: 2rhe - [20523] VL of Bence-Jones protein RHE |
Domain d3bjla1: 3bjl A:1-111 [20526] Other proteins in same PDB: d3bjla2, d3bjlb2 |
Domain d3bjlb1: 3bjl B:1-111 [20527] Other proteins in same PDB: d3bjla2, d3bjlb2 VL dimer of Bence-Jones protein LOC |
Domain d4bjla1: 4bjl A:1-111 [20528] Other proteins in same PDB: d4bjla2, d4bjlb2 |
Domain d4bjlb1: 4bjl B:1-111 [20529] Other proteins in same PDB: d4bjla2, d4bjlb2 VL dimer of Bence-Jones protein LOC |
Human (Homo sapiens), cluster 3.1 [TaxId:9606] [88537] (1 PDB entry) |
Domain d1aqkl1: 1aqk L:1-111 [20192] Other proteins in same PDB: d1aqkh1, d1aqkh2, d1aqkl2 part of Fab B7-15A2 |
Human (Homo sapiens), cluster 3.2 [TaxId:9606] [88538] (1 PDB entry) |
Domain d7fabl1: 7fab L:1-103 [19776] Other proteins in same PDB: d7fabh1, d7fabh2, d7fabl2 part of Fab NEW |
Human (Homo sapiens), cluster 4 [TaxId:9606] [88539] (23 PDB entries) |
Domain d1a8jh1: 1a8j H:1-111 [20598] Other proteins in same PDB: d1a8jh2, d1a8jl2 part of the antibody MCG light chain dimer complexed with pme |
Domain d1a8jl1: 1a8j L:1-111 [20597] Other proteins in same PDB: d1a8jh2, d1a8jl2 |
Domain d1dcla1: 1dcl A:1-111 [20565] Other proteins in same PDB: d1dcla2, d1dclb2 |
Domain d1dclb1: 1dcl B:1-111 [20566] Other proteins in same PDB: d1dcla2, d1dclb2 part of the antibody MCG light chain dimer |
Domain d1jvka1: 1jvk A:1-112 [71897] Other proteins in same PDB: d1jvka2, d1jvkb2 |
Domain d1jvkb1: 1jvk B:1-112 [71899] Other proteins in same PDB: d1jvka2, d1jvkb2 part of amyloidogenic protein BUR complexed with pca |
Domain d1lgva1: 1lgv A:1-112 [84608] Other proteins in same PDB: d1lgva2, d1lgvb2 |
Domain d1lgvb1: 1lgv B:1-112 [84610] Other proteins in same PDB: d1lgva2, d1lgvb2 part of amyloidogenic protein BUR complexed with pca |
Domain d1lhza1: 1lhz A:1-112 [84612] Other proteins in same PDB: d1lhza2, d1lhzb2 |
Domain d1lhzb1: 1lhz B:1-112 [84614] Other proteins in same PDB: d1lhza2, d1lhzb2 part of amyloidogenic protein BUR complexed with pca |
Domain d1mcba1: 1mcb A:1-111 [20575] Other proteins in same PDB: d1mcba2, d1mcbb2 |
Domain d1mcbb1: 1mcb B:1-111 [20576] Other proteins in same PDB: d1mcba2, d1mcbb2 part of the antibody MCG light chain dimer |
Domain d1mcca1: 1mcc A:1-111 [20583] Other proteins in same PDB: d1mcca2, d1mccb2 |
Domain d1mccb1: 1mcc B:1-111 [20584] Other proteins in same PDB: d1mcca2, d1mccb2 part of the antibody MCG light chain dimer complexed with nh2 |
Domain d1mcda1: 1mcd A:1-111 [20571] Other proteins in same PDB: d1mcda2, d1mcdb2 |
Domain d1mcdb1: 1mcd B:1-111 [20572] Other proteins in same PDB: d1mcda2, d1mcdb2 part of the antibody MCG light chain dimer complexed with bal, nh2 |
Domain d1mcea1: 1mce A:1-111 [20587] Other proteins in same PDB: d1mcea2, d1mceb2 |
Domain d1mceb1: 1mce B:1-111 [20588] Other proteins in same PDB: d1mcea2, d1mceb2 part of the antibody MCG light chain dimer complexed with bal |
Domain d1mcfa1: 1mcf A:1-111 [20579] Other proteins in same PDB: d1mcfa2, d1mcfb2 |
Domain d1mcfb1: 1mcf B:1-111 [20580] Other proteins in same PDB: d1mcfa2, d1mcfb2 part of the antibody MCG light chain dimer complexed with bal |
Domain d1mcha1: 1mch A:1-111 [20599] Other proteins in same PDB: d1mcha2, d1mchb2 |
Domain d1mchb1: 1mch B:1-111 [20600] Other proteins in same PDB: d1mcha2, d1mchb2 part of the antibody MCG light chain dimer complexed with bal |
Domain d1mcia1: 1mci A:1-111 [20581] Other proteins in same PDB: d1mcia2, d1mcib2 |
Domain d1mcib1: 1mci B:1-111 [20582] Other proteins in same PDB: d1mcia2, d1mcib2 part of the antibody MCG light chain dimer |
Domain d1mcja1: 1mcj A:1-111 [20595] Other proteins in same PDB: d1mcja2, d1mcjb2 |
Domain d1mcjb1: 1mcj B:1-111 [20596] Other proteins in same PDB: d1mcja2, d1mcjb2 part of the antibody MCG light chain dimer complexed with nh2 |
Domain d1mcka1: 1mck A:1-111 [20573] Other proteins in same PDB: d1mcka2, d1mckb2 |
Domain d1mckb1: 1mck B:1-111 [20574] Other proteins in same PDB: d1mcka2, d1mckb2 part of the antibody MCG light chain dimer complexed with nh2 |
Domain d1mcla1: 1mcl A:1-111 [20589] Other proteins in same PDB: d1mcla2, d1mclb2 |
Domain d1mclb1: 1mcl B:1-111 [20590] Other proteins in same PDB: d1mcla2, d1mclb2 part of the antibody MCG light chain dimer |
Domain d1mcna1: 1mcn A:1-111 [20591] Other proteins in same PDB: d1mcna2, d1mcnb2 |
Domain d1mcnb1: 1mcn B:1-111 [20592] Other proteins in same PDB: d1mcna2, d1mcnb2 part of the antibody MCG light chain dimer complexed with nh2 |
Domain d1mcqa1: 1mcq A:1-111 [20577] Other proteins in same PDB: d1mcqa2, d1mcqb2 |
Domain d1mcqb1: 1mcq B:1-111 [20578] Other proteins in same PDB: d1mcqa2, d1mcqb2 part of the antibody MCG light chain dimer complexed with nh2 |
Domain d1mcra1: 1mcr A:1-111 [20593] Other proteins in same PDB: d1mcra2, d1mcrb2 |
Domain d1mcrb1: 1mcr B:1-111 [20594] Other proteins in same PDB: d1mcra2, d1mcrb2 part of the antibody MCG light chain dimer |
Domain d1mcsa1: 1mcs A:1-111 [20585] Other proteins in same PDB: d1mcsa2, d1mcsb2 |
Domain d1mcsb1: 1mcs B:1-111 [20586] Other proteins in same PDB: d1mcsa2, d1mcsb2 part of the antibody MCG light chain dimer |
Domain d1mcwm1: 1mcw M:1-111 [20601] Other proteins in same PDB: d1mcwm2, d1mcww2 |
Domain d1mcww1: 1mcw W:1-111 [20602] Other proteins in same PDB: d1mcwm2, d1mcww2 part of heterologous L chain dimer MCG-WEIR |
Domain d2mcg11: 2mcg 1:1-111 [20567] Other proteins in same PDB: d2mcg12, d2mcg22 |
Domain d2mcg21: 2mcg 2:1-111 [20568] Other proteins in same PDB: d2mcg12, d2mcg22 part of the antibody MCG light chain dimer |
Domain d3mcg11: 3mcg 1:1-111 [20569] Other proteins in same PDB: d3mcg12, d3mcg22 |
Domain d3mcg21: 3mcg 2:1-111 [20570] Other proteins in same PDB: d3mcg12, d3mcg22 part of the antibody MCG light chain dimer |
Human (Homo sapiens), cluster 5 [TaxId:9606] [88540] (3 PDB entries) |
Domain d1lila1: 1lil A:2-107 [20557] Other proteins in same PDB: d1lila2, d1lilb2 |
Domain d1lilb1: 1lil B:2-107 [20558] Other proteins in same PDB: d1lila2, d1lilb2 part of Bence-Jones protein CLE |
Mouse (Mus musculus) [TaxId:10090] [88541] (25 PDB entries) |
Domain d1a6ul_: 1a6u L: [20254] Other proteins in same PDB: d1a6uh_ part of Fv B1-8 |
Domain d1a6vl_: 1a6v L: [20256] Other proteins in same PDB: d1a6vh_, d1a6vi_, d1a6vj_ |
Domain d1a6vm_: 1a6v M: [20258] Other proteins in same PDB: d1a6vh_, d1a6vi_, d1a6vj_ |
Domain d1a6vn_: 1a6v N: [20260] Other proteins in same PDB: d1a6vh_, d1a6vi_, d1a6vj_ part of Fv B1-8 complexed with npc |
Domain d1a6wl_: 1a6w L: [20252] Other proteins in same PDB: d1a6wh_ part of Fv B1-8 complexed with nip |
Domain d1dl7l_: 1dl7 L: [20498] Other proteins in same PDB: d1dl7h_ part of Fv M3C65; conflict: annotated in PDB as human protein complexed with nch |
Domain d1f4wl1: 1f4w L:1-110 [20452] Other proteins in same PDB: d1f4wh1, d1f4wh2, d1f4wl2 part of anti-carbohydrate Fab S-20-4 |
Domain d1f4xl1: 1f4x L:1-110 [20450] Other proteins in same PDB: d1f4xh1, d1f4xh2, d1f4xl2 part of anti-carbohydrate Fab S-20-4 complexed with mgs |
Domain d1f4yl1: 1f4y L:1-110 [20454] Other proteins in same PDB: d1f4yh1, d1f4yh2, d1f4yl2 part of anti-carbohydrate Fab S-20-4 complexed with mgu |
Domain d1gigl1: 1gig L:1-110 [19910] Other proteins in same PDB: d1gigh1, d1gigh2, d1gigl2 part of Fab HC19 |
Domain d1indl1: 1ind L:2-109 [19838] Other proteins in same PDB: d1indh1, d1indh2, d1indl2 part of Fab Cha255 complexed with eot, in |
Domain d1inel1: 1ine L:2-109 [19840] Other proteins in same PDB: d1ineh1, d1ineh2, d1inel2 part of Fab Cha255 complexed with eot, fe |
Domain d1jn6a1: 1jn6 A:1-108 [66923] Other proteins in same PDB: d1jn6a2, d1jn6b1, d1jn6b2 part of anti-estradiol Fab 10G6D6 |
Domain d1jnha1: 1jnh A:1-108 [66939] Other proteins in same PDB: d1jnha2, d1jnhb1, d1jnhb2, d1jnhc2, d1jnhd1, d1jnhd2, d1jnhe2, d1jnhf1, d1jnhf2, d1jnhg2, d1jnhh1, d1jnhh2 |
Domain d1jnhc1: 1jnh C:1-108 [66943] Other proteins in same PDB: d1jnha2, d1jnhb1, d1jnhb2, d1jnhc2, d1jnhd1, d1jnhd2, d1jnhe2, d1jnhf1, d1jnhf2, d1jnhg2, d1jnhh1, d1jnhh2 |
Domain d1jnhe1: 1jnh E:1-108 [66947] Other proteins in same PDB: d1jnha2, d1jnhb1, d1jnhb2, d1jnhc2, d1jnhd1, d1jnhd2, d1jnhe2, d1jnhf1, d1jnhf2, d1jnhg2, d1jnhh1, d1jnhh2 |
Domain d1jnhg1: 1jnh G:1-108 [66951] Other proteins in same PDB: d1jnha2, d1jnhb1, d1jnhb2, d1jnhc2, d1jnhd1, d1jnhd2, d1jnhe2, d1jnhf1, d1jnhf2, d1jnhg2, d1jnhh1, d1jnhh2 part of anti-estradiol Fab 10G6D6 complexed with eco |
Domain d1mfa_1: 1mfa 1L-111L [19888] Other proteins in same PDB: d1mfa_2 part of Fv SE155-4 complexed with abe, gal, mma |
Domain d1mfbl1: 1mfb L:1-111 [19890] Other proteins in same PDB: d1mfbh1, d1mfbh2, d1mfbl2 part of Fab SE155-4 complexed with abe, gal, man, ram |
Domain d1mfcl1: 1mfc L:1-111 [19894] Other proteins in same PDB: d1mfch1, d1mfch2, d1mfcl2 part of Fab SE155-4 complexed with abe, gal, man, ram |
Domain d1mfdl1: 1mfd L:1-111 [19896] Other proteins in same PDB: d1mfdh1, d1mfdh2, d1mfdl2 part of Fab SE155-4 complexed with abe, gal, mma |
Domain d1mfel1: 1mfe L:1-111 [19892] Other proteins in same PDB: d1mfeh1, d1mfeh2, d1mfel2 part of Fab SE155-4 complexed with abe, gal, man |
Domain d1ngpl1: 1ngp L:1-109 [20090] Other proteins in same PDB: d1ngph1, d1ngph2, d1ngpl2 part of Fab N1G9 complexed with npa, so4 |
Domain d1ngql1: 1ngq L:1-109 [20092] Other proteins in same PDB: d1ngqh1, d1ngqh2, d1ngql2 part of Fab N1G9 complexed with so4 |
Domain d1sm3l1: 1sm3 L:3-107 [20368] Other proteins in same PDB: d1sm3h1, d1sm3h2, d1sm3l2 part of tumor-specific Fab SM3 against epithelial mucin Muc1 complexed with cd, cl |
Domain d2vira1: 2vir A:1-110 [19916] Other proteins in same PDB: d2vira2, d2virb1, d2virb2, d2virc_ part of Fab HC19 complexed with zn |
Domain d2visa1: 2vis A:1-110 [19912] Other proteins in same PDB: d2visa2, d2visb1, d2visb2, d2visc_ part of Fab HC19 complexed with nag, zn; mutant |
Domain d2vita1: 2vit A:1-110 [19914] Other proteins in same PDB: d2vita2, d2vitb1, d2vitb2, d2vitc_ part of Fab HC19 complexed with zn; mutant |
Timeline for Protein Immunoglobulin light chain lambda variable domain, VL-lambda from b.1.1.1: V set domains (antibody variable domain-like):