SCOP 1.69: Domain d1qgda1: 1qgd A:333-527

Lineage for d1qgda1 (1qgd A:333-527)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.36: Thiamin diphosphate-binding fold (THDP-binding) [52517] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 213465

4. Superfamily c.36.1: Thiamin diphosphate-binding fold (THDP-binding) [52518] (8 families)
   there are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules
   two Pyr and two PP modules assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules

5. Family c.36.1.6: TK-like Pyr module [88735] (2 proteins)
   different order of the modules, PP module is N-terminal, Pyr module is next to it followed by a Rossmann-like domain

6. Protein Transketolase (TK), Pyr module [88736] (3 species)

7. Species Escherichia coli [TaxId:562] [89650] (1 PDB entry)

8. Domain d1qgda1: 1qgd A:333-527 [88367]
   Other proteins in same PDB: d1qgda2, d1qgda3, d1qgdb2, d1qgdb3

Details for d1qgda1

PDB Entry: 1qgd, 1.9 Å

PDB Description: transketolase from escherichia coli

SCOP Domain Sequences for d1qgda1:

Sequence; same for both SEQRES and ATOM records:

>d1qgda1 c.36.1.6 (A:333-527) Transketolase (TK), Pyr module {Escherichia coli}
mpsdfdakakefiaklqanpakiasrkasqnaieafgpllpeflggsadlapsnltlwsg
skainedaagnyihygvrefgmtaiangislhggflpytstflmfveyarnavrmaalmk
qrqvmvythdsiglgedgpthqpveqvaslrvtpnmstwrpcdqvesavawkygverqdg
ptalilsrqnlaqqe

Timeline for d1qgda1:

• d1qgda1 first appeared in SCOP 1.65
  
• d1qgda1 appears in SCOP 1.67
  
• d1qgda1 appears in SCOP 1.71
  
• d1qgda1 appears in the current release, SCOPe 2.08