SCOP 1.75: Domain d1pf4a2: 1pf4 A:10-320

Lineage for d1pf4a2 (1pf4 A:10-320)

1. Root: SCOP 1.75

2. Class f: Membrane and cell surface proteins and peptides [56835] (58 folds)

3. Fold f.37: ABC transporter transmembrane region [90122] (1 superfamily)
   multihelical; complex architecture with several transmembrane helices

4. Superfamily f.37.1: ABC transporter transmembrane region [90123] (1 family)

5. Family f.37.1.1: ABC transporter transmembrane region [90124] (2 proteins)

6. Protein Multidrug resistance ABC transporter MsbA, N-terminal domain [90125] (2 species)
   a low-resolution structure of the E.coli MsbA in an open conformation is also available (f.35.1.1)
   a low-resolution structure of the E.coli MsbA in an open conformation is also available (f.35.1.1)

7. Species Vibrio cholerae [TaxId:666] [90126] (1 PDB entry)

8. Domain d1pf4a2: 1pf4 A:10-320 [88053]
   Other proteins in same PDB: d1pf4a1, d1pf4b1, d1pf4c1, d1pf4d1
   structure in a closed conformation

Details for d1pf4a2

PDB Entry: 1pf4, 3.8 Å

PDB Description: Structure of MsbA from Vibrio cholera: A Multidrug Resistance ABC Transporter Homolog in a Closed Conformation

PDB Compounds: (A:) transport ATP-binding protein MsbA

SCOP Domain Sequences for d1pf4a2:

Sequence, based on SEQRES records:

>d1pf4a2 f.37.1.1 (A:10-320) Multidrug resistance ABC transporter MsbA, N-terminal domain {Vibrio cholerae [TaxId: 666]}
wqtfkrlwtyirlykaglvvstialvinaaadtymisllkplldegfgnaesnflrilpf
milglmfvrglsgfassyclswvsgnvvmqmrrrlfnhfmhmpvrffdqestggllsrit
ydseqvagatsralvsivregasiiglltlmfwnswqlslvlivvapvvafaisfvskrf
rkisrnmqtamghvtssaeqmlkghkvvlsyggqeverkrfdkvsnsmrqqtmklvsaqs
iadpviqmiaslalfavlflasvdsiraeltpgtftvvfsamfglmrplkaltsvtsefq
rgmaacqtlfg

Sequence, based on observed residues (ATOM records):

>d1pf4a2 f.37.1.1 (A:10-320) Multidrug resistance ABC transporter MsbA, N-terminal domain {Vibrio cholerae [TaxId: 666]}
wqtfkrlwtyirlykaglvvstialvinaaadtymisllkplldegfgnaesnflrilpf
milglmfvrglsgfassyclswvsgnvvmqmrrrlfnhfmhmpvrffdqestggllsrit
ydseqvagatsralvsivregasiiglltlmfwnswqlslvlivvapvvafaisfvskrf
rkisrnmqtamghrqqtmklvsaqsiadpviqmiaslalfavlflasvdsiraeltpgtf
tvvfsamfglmrplkaltsvtsefqrgmaacqtlfg

Timeline for d1pf4a2:

• d1pf4a2 first appeared in SCOP 1.65
  
• d1pf4a2 appears in SCOP 1.73
  
• d1pf4a2 does not appear in SCOPe 2.01