SCOP 1.67: Domain d1pdsa_: 1pds A:

Lineage for d1pdsa_ (1pds A:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (11 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (40 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7

6. Protein Negative transcriptional regulator NmrA [69407] (1 species)
   has an UDP-galactose 4-epimerase-like structure but evolved a different function

7. Species Aspergillus nidulans [TaxId:162425] [69408] (4 PDB entries)

8. Domain d1pdsa_: 1pds A: [88033]
   complexed with cl, nap

Details for d1pdsa_

PDB Entry: 1pds, 1.7 Å

PDB Description: Crystal Structure of NmrA, a Negative Transcriptional Regulator, in Complex with NADP at 1.7A Resolution

SCOP Domain Sequences for d1pdsa_:

Sequence, based on SEQRES records:

>d1pdsa_ c.2.1.2 (A:) Negative transcriptional regulator NmrA {Aspergillus nidulans}
qqkktiavvnatgrqaaslirvaaavghhvraqvhslkgliaeelqaipnvtlfqgplln
nvplmdtlfegahlafinttsqagdeiaigkdladaakragtiqhyiyssmpdhslygpw
pavpmwapkftvenyvrqlglpstfvyagiynnnftslpyplfqmelmpdgtfewhapfd
pdiplpwldaehdvgpallqifkdgpqkwnghrialtfetlspvqvcaafsralnrrvty
vqvpkveikvnipvgyreqleaievvfgehkapyfplpefsrpaagspkglgpangkgag
agmmqgpggvisqrvtdearklwsgwrdmeeyarevfpieeeangldwml

Sequence, based on observed residues (ATOM records):

>d1pdsa_ c.2.1.2 (A:) Negative transcriptional regulator NmrA {Aspergillus nidulans}
qqkktiavvnatgrqaaslirvaaavghhvraqvhslkgliaeelqaipnvtlfqgplln
nvplmdtlfegahlafinttsqagdeiaigkdladaakragtiqhyiyssmpdhslygpw
pavpmwapkftvenyvrqlglpstfvyagiynnnftslpyplfqmelmpdgtfewhapfd
pdiplpwldaehdvgpallqifkdgpqkwnghrialtfetlspvqvcaafsralnrrvty
vqvpkveikvnipvgyreqleaievvfgehkapyfplpefsggvisqrvtdearklwsgw
rdmeeyarevfpieeeangldwml

Timeline for d1pdsa_:

• d1pdsa_ first appeared in SCOP 1.65
  
• d1pdsa_ does not appear in SCOP 1.69