SCOP 1.65: Domain d1p8db_: 1p8d B:

Lineage for d1p8db_ (1p8d B:)

1. Root: SCOP 1.65

2. Class a: All alpha proteins [46456] (179 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (25 proteins)

6. Protein Oxysterols receptor LXR-beta [89149] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89150] (1 PDB entry)

8. Domain d1p8db_: 1p8d B: [87942]
   complexed with a co-activator peptide, chains C and D
   complexed with co1

Details for d1p8db_

PDB Entry: 1p8d, 2.8 Å

PDB Description: x-ray crystal structure of lxr ligand binding domain with 24(s),25- epoxycholesterol

SCOP Domain Sequences for d1p8db_:

Sequence, based on SEQRES records:

>d1p8db_ a.123.1.1 (B:) Oxysterols receptor LXR-beta {Human (Homo sapiens)}
vqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpqsrdarqqrfahftelaii
svqeivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftysk
ddfhraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqq
pyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiw
dv

Sequence, based on observed residues (ATOM records):

>d1p8db_ a.123.1.1 (B:) Oxysterols receptor LXR-beta {Human (Homo sapiens)}
vqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgasrdarqqrfahftelaiisvq
eivdfakqvpgflqlgredqiallkastieimlletarrynhetecitflkdftyskddf
hraglqvefinpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyv
eallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdv

Timeline for d1p8db_:

• d1p8db_ is new in SCOP 1.65
  
• d1p8db_ appears in SCOP 1.67
  
• d1p8db_ appears in the current release, SCOPe 2.08