SCOPe 2.04: Domain d1p5eb1: 1p5e B:175-309

Lineage for d1p5eb1 (1p5e B:175-309)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.74: Cyclin-like [47953] (1 superfamily)
   core: 5 helices; one helix is surrounded by the others

4. Superfamily a.74.1: Cyclin-like [47954] (4 families)
   duplication: consists of two domains of this fold

5. Family a.74.1.1: Cyclin [47955] (9 proteins)

6. Protein Cyclin A [47956] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [47957] (74 PDB entries)
   Uniprot P20248 175-432

8. Domain d1p5eb1: 1p5e B:175-309 [87797]
   Other proteins in same PDB: d1p5ea_, d1p5ec_
   complexed with tbs

Details for d1p5eb1

PDB Entry: 1p5e, 2.22 Å

PDB Description: the structure of phospho-cdk2/cyclin a in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (tbs)

PDB Compounds: (B:) cyclin a2

SCOPe Domain Sequences for d1p5eb1:

Sequence; same for both SEQRES and ATOM records:

>d1p5eb1 a.74.1.1 (B:175-309) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}
vpdyhedihtylremevkckpkvgymkkqpditnsmrailvdwlvevgeeyklqnetlhl
avnyidrflssmsvlrgklqlvgtaamllaskfeeiyppevaefvyitddtytkkqvlrm
ehlvlkvltfdlaap

Timeline for d1p5eb1:

• d1p5eb1 first appeared in SCOP 1.65
  
• d1p5eb1 appears in SCOPe 2.03
  
• d1p5eb1 appears in SCOPe 2.05
  
• d1p5eb1 appears in the current release, SCOPe 2.08