Lineage for d1p22a2 (1p22 A:253-545)

  1. Root: SCOP 1.73
  2. 651986Class b: All beta proteins [48724] (165 folds)
  3. 675262Fold b.69: 7-bladed beta-propeller [50964] (14 superfamilies)
    consists of seven 4-stranded beta-sheet motifs; meander
  4. 675344Superfamily b.69.4: WD40 repeat-like [50978] (2 families) (S)
    also contains 8-bladed propellers
  5. 675345Family b.69.4.1: WD40-repeat [50979] (8 proteins)
    this is a repeat family; one repeat unit is 1tyq C:201-243 found in domain
  6. 675395Protein F-box/WD-repeat protein 1 (beta-TRCP1) [89376] (1 species)
  7. 675396Species Human (Homo sapiens) [TaxId:9606] [89377] (1 PDB entry)
  8. 675397Domain d1p22a2: 1p22 A:253-545 [87716]
    Other proteins in same PDB: d1p22a1, d1p22b1, d1p22b2
    complexed with sep

Details for d1p22a2

PDB Entry: 1p22 (more details), 2.95 Å

PDB Description: Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity on the SCFbeta-TrCP1 ubiquitin ligase
PDB Compounds: (A:) F-box/WD-repeat protein 1A

SCOP Domain Sequences for d1p22a2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1p22a2 b.69.4.1 (A:253-545) F-box/WD-repeat protein 1 (beta-TRCP1) {Human (Homo sapiens) [TaxId: 9606]}
grhslqrihcrsetskgvyclqyddqkivsglrdntikiwdkntleckriltghtgsvlc
lqyderviitgssdstvrvwdvntgemlntlihhceavlhlrfnngmmvtcskdrsiavw
dmasptditlrrvlvghraavnvvdfddkyivsasgdrtikvwntstcefvrtlnghkrg
iaclqyrdrlvvsgssdntirlwdiecgaclrvlegheelvrcirfdnkrivsgaydgki
kvwdlvaaldprapagtlclrtlvehsgrvfrlqfdefqivssshddtiliwd

SCOP Domain Coordinates for d1p22a2:

Click to download the PDB-style file with coordinates for d1p22a2.
(The format of our PDB-style files is described here.)

Timeline for d1p22a2:

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Domains from same chain:
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d1p22a1