Lineage for d1opka2 (1opk A:140-240)

  1. Root: SCOPe 2.03
  2. 1396887Class d: Alpha and beta proteins (a+b) [53931] (376 folds)
  3. 1424633Fold d.93: SH2-like [55549] (1 superfamily)
    3 layers: a/b/a; antiparallel beta-sheet of 5 strands is flaked by two helices
  4. 1424634Superfamily d.93.1: SH2 domain [55550] (2 families) (S)
  5. 1424635Family d.93.1.1: SH2 domain [55551] (35 proteins)
    Pfam PF00017
  6. 1424636Protein Abl tyrosine kinase [55581] (2 species)
  7. 1424641Species Mouse (Mus musculus) [TaxId:10090] [89998] (1 PDB entry)
  8. 1424642Domain d1opka2: 1opk A:140-240 [87233]
    Other proteins in same PDB: d1opka1, d1opka3
    complexed with gol, myr, p16

Details for d1opka2

PDB Entry: 1opk (more details), 1.8 Å

PDB Description: Structural basis for the auto-inhibition of c-Abl tyrosine kinase
PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d1opka2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1opka2 d.93.1.1 (A:140-240) Abl tyrosine kinase {Mouse (Mus musculus) [TaxId: 10090]}
slekhswyhgpvsrnaaeyllssgingsflvresesspgqrsislryegrvyhyrintas
dgklyvssesrfntlaelvhhhstvadglittlhypapkrn

SCOPe Domain Coordinates for d1opka2:

Click to download the PDB-style file with coordinates for d1opka2.
(The format of our PDB-style files is described here.)

Timeline for d1opka2: