SCOPe 2.01: Domain d1opja_: 1opj A:

Lineage for d1opja_ (1opj A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Abelsone tyrosine kinase (abl) [56166] (1 species)
   PTK group; Abl subfamily; non-membrane spanning protein tyrosine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56167] (9 PDB entries)

8. Domain d1opja_: 1opj A: [87230]
   complexed with cl, myr, sti

Details for d1opja_

PDB Entry: 1opj, 1.75 Å

PDB Description: Structural basis for the auto-inhibition of c-Abl tyrosine kinase

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d1opja_:

Sequence; same for both SEQRES and ATOM records:

>d1opja_ d.144.1.7 (A:) Abelsone tyrosine kinase (abl) {Mouse (Mus musculus) [TaxId: 10090]}
amdpsspnydkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveef
lkeaavmkeikhpnlvqllgvctreppfyiitefmtygnlldylrecnrqevsavvllym
atqissameylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpi
kwtapeslaynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpeg
cpekvyelmracwqwnpsdrpsfaeihqafetmfqessisdevekel

Timeline for d1opja_:

• d1opja_ first appeared in SCOP 1.65
  
• d1opja_ appears in SCOP 1.75
  
• d1opja_ appears in SCOPe 2.02
  
• d1opja_ appears in the current release, SCOPe 2.08, called d1opja1