Lineage for d1op5m2 (1op5 M:116-229)

  1. Root: SCOPe 2.02
  2. 1103260Class b: All beta proteins [48724] (174 folds)
  3. 1103261Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 1103262Superfamily b.1.1: Immunoglobulin [48726] (5 families) (S)
  5. 1105902Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)
  6. 1107361Protein Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma [88574] (6 species)
  7. 1107365Species Human (Homo sapiens) [TaxId:9606] [88575] (172 PDB entries)
    including humanized antibodies (chimeric proteins with human constant domains)
    Uniprot Q6N089 20-243 # 95% sequence identity; natural chimera: antibody heavy chain (Fab HYB3) ! SQ NA # humanized antibody ! Uniprot P01857 # IGHG1_HUMAN Ig gamma-1 chain C region ! SQ NA # engineered antibody
  8. 1107631Domain d1op5m2: 1op5 M:116-229 [87223]
    Other proteins in same PDB: d1op5h1, d1op5k1, d1op5k2, d1op5l1, d1op5l2, d1op5m1
    part of Fab 2G12
    complexed with man

Details for d1op5m2

PDB Entry: 1op5 (more details), 3 Å

PDB Description: crystal structure of fab 2g12 bound to man9glcnac2
PDB Compounds: (M:) FAB 2G12, heavy chain

SCOPe Domain Sequences for d1op5m2:

Sequence; same for both SEQRES and ATOM records: (download)

>d1op5m2 b.1.1.2 (M:116-229) Immunoglobulin heavy chain gamma constant domain 1, CH1-gamma {Human (Homo sapiens) [TaxId: 9606]}
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepks

SCOPe Domain Coordinates for d1op5m2:

Click to download the PDB-style file with coordinates for d1op5m2.
(The format of our PDB-style files is described here.)

Timeline for d1op5m2: