Lineage for d1op5m1 (1op5 M:1-115)

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 546419Superfamily b.1.1: Immunoglobulin [48726] (4 families) (S)
  5. 546420Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (28 proteins)
  6. 546556Protein Immunoglobulin heavy chain variable domain, VH [88543] (20 species)
    VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species
  7. 546557Species Engineered (including hybrid species) [88562] (52 PDB entries)
  8. 546626Domain d1op5m1: 1op5 M:1-115 [87222]
    Other proteins in same PDB: d1op5h2, d1op5k1, d1op5k2, d1op5l1, d1op5l2, d1op5m2
    part of engineered Fab 2G12
    complexed with man, nag

Details for d1op5m1

PDB Entry: 1op5 (more details), 3 Å

PDB Description: crystal structure of fab 2g12 bound to man9glcnac2

SCOP Domain Sequences for d1op5m1:

Sequence; same for both SEQRES and ATOM records: (download)

>d1op5m1 b.1.1.1 (M:1-115) Immunoglobulin heavy chain variable domain, VH {Engineered (including hybrid species)}

SCOP Domain Coordinates for d1op5m1:

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Timeline for d1op5m1: