SCOP 1.69: Domain d1ogsb2: 1ogs B:78-431

Lineage for d1ogsb2 (1ogs B:78-431)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (31 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.8: (Trans)glycosidases [51445] (11 families)

5. Family c.1.8.3: beta-glycanases [51487] (22 proteins)
   consist of a number of sequence families

6. Protein Glucosylceramidase, catalytic domain [89473] (1 species)
   acid-beta-glucosidase; glycosyl hydrolase family 30; contains additional beta-domain similar to one found in alpha amylases

7. Species Human (Homo sapiens) [TaxId:9606] [89474] (1 PDB entry)

8. Domain d1ogsb2: 1ogs B:78-431 [87000]
   Other proteins in same PDB: d1ogsa1, d1ogsb1

Details for d1ogsb2

PDB Entry: 1ogs, 2 Å

PDB Description: human acid-beta-glucosidase

SCOP Domain Sequences for d1ogsb2:

Sequence; same for both SEQRES and ATOM records:

>d1ogsb2 c.1.8.3 (B:78-431) Glucosylceramidase, catalytic domain {Human (Homo sapiens)}
vkgfggamtdaaalnilalsppaqnlllksyfseegigyniirvpmascdfsirtytyad
tpddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwtsptwlktngavngkgsl
kgqpgdiyhqtwaryfvkfldayaehklqfwavtaenepsagllsgypfqclgftpehqr
dfiardlgptlansthhnvrllmlddqrlllphwakvvltdpeaakyvhgiavhwyldfl
apakatlgethrlfpntmlfaseacvgskfweqsvrlgswdrgmqyshsiitnllyhvvg
wtdwnlalnpeggpnwvrnfvdspiivditkdtfykqpmfyhlghfskfipegs

Timeline for d1ogsb2:

• d1ogsb2 first appeared in SCOP 1.65
  
• d1ogsb2 appears in SCOP 1.67
  
• d1ogsb2 appears in SCOP 1.71
  
• d1ogsb2 appears in the current release, SCOPe 2.08