SCOPe 2.08: Domain d1obca3: 1obc A:1-225,A:418-686

Lineage for d1obca3 (1obc A:1-225,A:418-686)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.1: Class I aminoacyl-tRNA synthetases (RS), catalytic domain [52375] (13 proteins)
   contains a conserved all-alpha subdomain at the C-terminal extension

6. Protein Leucyl-tRNA synthetase (LeuRS) [82356] (1 species)

7. Species Thermus thermophilus [TaxId:274] [82357] (3 PDB entries)
   contains a non-conserved insertion (residues 581-633) that forms a separate subdomain; possible rudiment Zn finger

8. Domain d1obca3: 1obc A:1-225,A:418-686 [86766]
   Other proteins in same PDB: d1obca1, d1obca2
   protein/RNA complex; complexed with 2ad, leu, lms, nva, zn

Details for d1obca3

PDB Entry: 1obc, 2.1 Å

PDB Description: leucyl-trna synthetase from thermus thermophilus complexed with a post-transfer editing substrate analogue

PDB Compounds: (A:) leucyl-tRNA synthetase

SCOPe Domain Sequences for d1obca3:

Sequence, based on SEQRES records:

>d1obca3 c.26.1.1 (A:1-225,A:418-686) Leucyl-tRNA synthetase (LeuRS) {Thermus thermophilus [TaxId: 274]}
mekynphaieakwqrfweekgfmkakdlpggrgkqyvlvmfpypsgdlhmghlknytmgd
vlarfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilyd
wdrevttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhe
dtpvekreleqwylritayaerllkdleglnwpekvkamqrawigXrlrdwlisrqrywg
tpipmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefyettcpkcggpa
krdtdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggvehavlhllysrf
ftkflhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptrirleipesals
ledvrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadiaritilfaappe
nemvwteegvqgawr

Sequence, based on observed residues (ATOM records):

>d1obca3 c.26.1.1 (A:1-225,A:418-686) Leucyl-tRNA synthetase (LeuRS) {Thermus thermophilus [TaxId: 274]}
mekynphaieakwqrfweekgfmkakdlpgkqyvlvmfpypsgdlhmghlknytmgdvla
rfrrmqgyevlhpmgwdafglpaenaalkfgvhpkdwtyanirqakeslrlmgilydwdr
evttcepeyyrwnqwiflkmwekglayrakglvnwcpkcqtvlaneqvvegrcwrhedtp
vekreleqwylritayaerllkdleglnwpekvkamqrawigXrlrdwlisrqrywgtpi
pmvhceacgvvpvpeeelpvllpdlkdvedirpkgkspleahpefyettcpkcggpakrd
tdtmdtffdsswyylrytdphndrlpfdpekanawmpvdqyiggvehavlhllysrfftk
flhdlgmvkveepfqglftqgmvlawtdfgpvevegsvvrlpeptrirleipesalsled
vrkmgaelrphedgtlhlwkpavmskskgngvmvgpfvkeqgadiaritilfaappenem
vwteegvqgawr

Timeline for d1obca3:

• d1obca3 first appeared in SCOP 1.65
  
• d1obca3 appears in SCOPe 2.07