SCOPe 2.01: Domain d1nyxb_: 1nyx B:

Lineage for d1nyxb_ (1nyx B:)

1. Root: SCOPe 2.01

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (59 PDB entries)
   Uniprot P37231 232-505

8. Domain d1nyxb_: 1nyx B: [86432]
   complexed with drf

Details for d1nyxb_

PDB Entry: 1nyx, 2.65 Å

PDB Description: Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist

PDB Compounds: (B:) Peroxisome proliferator activated receptor gamma

SCOPe Domain Sequences for d1nyxb_:

Sequence, based on SEQRES records:

>d1nyxb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykdl

Sequence, based on observed residues (ATOM records):

>d1nyxb_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itvairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslm
nkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviils
gdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllq
vikktethpllqeiykdl

Timeline for d1nyxb_:

• d1nyxb_ first appeared in SCOP 1.65
  
• d1nyxb_ appears in SCOP 1.75
  
• d1nyxb_ appears in SCOPe 2.02
  
• d1nyxb_ appears in the current release, SCOPe 2.08