SCOP 1.69: Domain d1nqth1: 1nqt H:209-501

Lineage for d1nqth1 (1nqt H:209-501)

1. Root: SCOP 1.69

2. Class c: Alpha and beta proteins (a/b) [51349] (136 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (12 families)

5. Family c.2.1.7: Aminoacid dehydrogenase-like, C-terminal domain [51883] (11 proteins)
   extra N-terminal helix displaces the C-terminal helix (following strand 6) from its usual position creating a family nicotineamide-binding site

6. Protein Glutamate dehydrogenase [51884] (7 species)

7. Species Cow (Bos taurus) [TaxId:9913] [51889] (5 PDB entries)

8. Domain d1nqth1: 1nqt H:209-501 [86066]
   Other proteins in same PDB: d1nqta2, d1nqtb2, d1nqtc2, d1nqtd2, d1nqte2, d1nqtf2, d1nqtg2, d1nqth2, d1nqti2, d1nqtj2, d1nqtk2, d1nqtl2

Details for d1nqth1

PDB Entry: 1nqt, 3.5 Å

PDB Description: crystal structure of bovine glutamate dehydrogenase-adp complex

SCOP Domain Sequences for d1nqth1:

Sequence; same for both SEQRES and ATOM records:

>d1nqth1 c.2.1.7 (H:209-501) Glutamate dehydrogenase {Cow (Bos taurus)}
hgrisatgrgvfhgienfineasymsilgmtpgfgdktfvvqgfgnvglhsmrylhrfga
kciavgesdgsiwnpdgidpkeledfklqhgsilgfpkakpyegsileadcdilipaase
kqltksnaprvkakiiaegangpttpeadkiflernimvipdlylnaggvtvsyfewlkn
lnhvsygrltfkyerdsnyhllmsvqeslerkfgkhggtipivptaefqdrisgasekdi
vhsglaytmersarqimrtamkynlgldlrtaayvnaiekvfkvyneagvtft

Timeline for d1nqth1:

• d1nqth1 first appeared in SCOP 1.65
  
• d1nqth1 appears in SCOP 1.67
  
• d1nqth1 appears in SCOP 1.71
  
• d1nqth1 appears in the current release, SCOPe 2.08