Lineage for d1np0b2 (1np0 B:55-199)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2204982Fold d.92: Zincin-like [55485] (2 superfamilies)
    contains mixed beta sheet with connection over free side of the sheet
  4. 2206336Superfamily d.92.2: beta-N-acetylhexosaminidase-like domain [55545] (4 families) (S)
    contains similar fold but lacks its catalytic centre
  5. 2206337Family d.92.2.1: beta-N-acetylhexosaminidase domain [55546] (4 proteins)
    family GH20
  6. 2206354Protein beta-hexosaminidase B, N-terminal domain [89992] (1 species)
  7. 2206355Species Human (Homo sapiens) [TaxId:9606] [89993] (6 PDB entries)
  8. 2206367Domain d1np0b2: 1np0 B:55-199 [85943]
    Other proteins in same PDB: d1np0a1, d1np0b1
    complexed with gol, ngt, so4

Details for d1np0b2

PDB Entry: 1np0 (more details), 2.5 Å

PDB Description: human lysosomal beta-hexosaminidase isoform b in complex with intermediate analogue nag-thiazoline
PDB Compounds: (B:) beta-hexosaminidase beta chain

SCOPe Domain Sequences for d1np0b2:

Sequence, based on SEQRES records: (download)

>d1np0b2 d.92.2.1 (B:55-199) beta-hexosaminidase B, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
alwplplsvkmtpnllhlapenfyishspnstagpsctlleeafrryhgyifgfykwhhe
paefqaktqvqqllvsitlqsecdafpnissdesytllvkepvavlkanrvwgalrglet
fsqlvyqdsygtftinestiidspr

Sequence, based on observed residues (ATOM records): (download)

>d1np0b2 d.92.2.1 (B:55-199) beta-hexosaminidase B, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
alwplplsvkmtpnllhlapenfyishspnstagpsctlleeafrryhgyifgtqvqqll
vsitlqsecdafpnissdesytllvkepvavlkanrvwgalrgletfsqlvyqdsygtft
inestiidspr

SCOPe Domain Coordinates for d1np0b2:

Click to download the PDB-style file with coordinates for d1np0b2.
(The format of our PDB-style files is described here.)

Timeline for d1np0b2:

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Domains from same chain:
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d1np0b1