SCOP 1.67: Domain d1mx5b_: 1mx5 B:

Lineage for d1mx5b_ (1mx5 B:)

1. Root: SCOP 1.67

2. Class c: Alpha and beta proteins (a/b) [51349] (130 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (30 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (5 proteins)

6. Protein Mammalian carboxylesterase (liver carboxylesterase I) [75282] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89768] (3 PDB entries)

8. Domain d1mx5b_: 1mx5 B: [85172]

Details for d1mx5b_

PDB Entry: 1mx5, 2.8 Å

PDB Description: crystal structure of human liver carboxylesterase in complexed with homatropine, a cocaine analogue

SCOP Domain Sequences for d1mx5b_:

Sequence; same for both SEQRES and ATOM records:

>d1mx5b_ c.69.1.1 (B:) Mammalian carboxylesterase (liver carboxylesterase I) {Human (Homo sapiens)}
sppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvknat
syppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwihg
gglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrwv
qdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgdv
kplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllgt
vidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsll
wksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdaga
ptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwan
farngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

Timeline for d1mx5b_:

• d1mx5b_ first appeared in SCOP 1.65
  
• d1mx5b_ appears in SCOP 1.69
  
• d1mx5b_ appears in the current release, SCOPe 2.08