SCOP 1.65: Domain d1mx1b_: 1mx1 B:

Lineage for d1mx1b_ (1mx1 B:)

1. Root: SCOP 1.65

2. Class c: Alpha and beta proteins (a/b) [51349] (121 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (26 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (4 proteins)

6. Protein Mammalian carboxylesterase (liver carboxylesterase I) [75282] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89768] (3 PDB entries)

8. Domain d1mx1b_: 1mx1 B: [85166]

Details for d1mx1b_

PDB Entry: 1mx1, 2.4 Å

PDB Description: crystal structure of human liver carboxylesterase in complex with tacrine

SCOP Domain Sequences for d1mx1b_:

Sequence; same for both SEQRES and ATOM records:

>d1mx1b_ c.69.1.1 (B:) Mammalian carboxylesterase (liver carboxylesterase I) {Human (Homo sapiens)}
sppvvdtvhgkvlgkfvslegfaqpvaiflgipfakpplgplrftppqpaepwsfvknat
syppmctqdpkagqllselftnrkeniplklsedclylniytpadltkknrlpvmvwihg
gglmvgaastydglalaahenvvvvtiqyrlgiwgffstgdehsrgnwghldqvaalrwv
qdniasfggnpgsvtifgesaggesvsvlvlsplaknlfhraisesgvaltsvlvkkgdv
kplaeqiaitagcktttsavmvhclrqkteeellettlkmkflsldlqgdpresqpllgt
vidgmlllktpeelqaernfhtvpymvginkqefgwlipmlmsyplsegqldqktamsll
wksyplvciakelipeatekylggtddtvkkkdlfldliadvmfgvpsvivarnhrdaga
ptymyefqyrpsfssdmkpktvigdhgdelfsvfgapflkegaseeeirlskmvmkfwan
farngnpngeglphwpeynqkegylqigantqaaqklkdkevafwtnlfak

Timeline for d1mx1b_:

• d1mx1b_ is new in SCOP 1.65
  
• d1mx1b_ appears in SCOP 1.67
  
• d1mx1b_ appears in the current release, SCOPe 2.08