SCOPe 2.06: Domain d1ms1a2: 1ms1 A:1-399

Lineage for d1ms1a2 (1ms1 A:1-399)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
   consists of six 4-stranded beta-sheet motifs; meander

4. Superfamily b.68.1: Sialidases [50939] (3 families)

5. Family b.68.1.1: Sialidases (neuraminidases) [50940] (10 proteins)

6. Protein Trypanosoma sialidase [82164] (2 species)

7. Species Trypanosoma cruzi [TaxId:5693] [89371] (13 PDB entries)
   Uniprot Q26966

8. Domain d1ms1a2: 1ms1 A:1-399 [85065]
   Other proteins in same PDB: d1ms1a1, d1ms1b1
   complexed with dan, gol

Details for d1ms1a2

PDB Entry: 1ms1, 1.8 Å

PDB Description: monoclinic form of trypanosoma cruzi trans-sialidase, in complex with 3-deoxy-2,3-dehydro-n-acetylneuraminic acid (dana)

PDB Compounds: (A:) Trans-sialidase

SCOPe Domain Sequences for d1ms1a2:

Sequence; same for both SEQRES and ATOM records:

>d1ms1a2 b.68.1.1 (A:1-399) Trypanosoma sialidase {Trypanosoma cruzi [TaxId: 5693]}
lapgssrvelfkrqsskvpfekdgkvtervvhsfrlpalvnvdgvmvaiadaryetsfdn
slidtvakysvddgetwetqiaiknsrassvsrvvdptvivkgnklyvlvgsynssrsyw
tshgdardwdillavgevtkstaggkitasikwgspvslkeffpaemegmhtnqflggag
vaivasngnlvypvqvtnkkkqvfskifysedegktwkfgkgrsafgcsepvalewegkl
iintrvdyrrrlvyessdmgntwleavgtlsrvwgpspksnqpgsqssftavtiegmrvm
lfthplnfkgrwlrdrlnlwltdnqriynvgqvsigdensayssvlykddklyclheins
nevyslvfarlvgelriiksvlqswknwdshlssictpa

Timeline for d1ms1a2:

• d1ms1a2 first appeared in SCOP 1.65
  
• d1ms1a2 appears in SCOPe 2.05
  
• d1ms1a2 appears in SCOPe 2.07
  
• d1ms1a2 appears in the current release, SCOPe 2.08