SCOP 1.75: Domain d1leib2: 1lei B:39-250

Lineage for d1leib2 (1lei B:39-250)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.2: Common fold of diphtheria toxin/transcription factors/cytochrome f [49379] (10 superfamilies)
   sandwich; 9 strands in 2 sheet; greek-key; subclass of immunoglobin-like fold

4. Superfamily b.2.5: p53-like transcription factors [49417] (7 families)

5. Family b.2.5.3: Rel/Dorsal transcription factors, DNA-binding domain [81315] (6 proteins)

6. Protein p50 subunit of NF-kappa B (NFKB), N-terminal domain [49423] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [49425] (8 PDB entries)

8. Domain d1leib2: 1lei B:39-250 [84602]
   Other proteins in same PDB: d1leia1, d1leia2, d1leib1
   complexed with 5it

Details for d1leib2

PDB Entry: 1lei, 2.7 Å

PDB Description: the kb dna sequence from the hlv-ltr functions as an allosteric regulator of hiv transcription

PDB Compounds: (B:) nuclear factor nf-kappa-b p50 subunit

SCOP Domain Sequences for d1leib2:

Sequence; same for both SEQRES and ATOM records:

>d1leib2 b.2.5.3 (B:39-250) p50 subunit of NF-kappa B (NFKB), N-terminal domain {Mouse (Mus musculus) [TaxId: 10090]}
gpylqileqpkqrgfrfryvcegpshgglpgasseknkksypqvkicnyvgpakvivqlv
tngknihlhahslvgkhcedgvctvtagpkdmvvgfanlgilhvtkkkvfetlearmtea
cirgynpgllvhsdlaylqaegggdrqltdrekeiirqaavqqtkemdlsvvrlmftafl
pdstgsftrrlepvvsdaiydskapnasnlki

Timeline for d1leib2:

• d1leib2 first appeared in SCOP 1.65
  
• d1leib2 appears in SCOP 1.73
  
• d1leib2 appears in SCOPe 2.01
  
• d1leib2 appears in the current release, SCOPe 2.08