SCOP 1.73: Domain d1jwsb1: 1jws B:93-190

Lineage for d1jwsb1 (1jws B:93-190)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (27 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88628] (38 PDB entries)
   probably orthologous to the mouse I-E group

8. Domain d1jwsb1: 1jws B:93-190 [84244]
   Other proteins in same PDB: d1jwsa1, d1jwsa2, d1jwsb2, d1jwsd1, d1jwsd2
   mutant

Details for d1jwsb1

PDB Entry: 1jws, 2.6 Å

PDB Description: crystal structure of the complex of the mhc class ii molecule hla-dr1 (ha peptide 306-318) with the superantigen sec3 variant 3b1

PDB Compounds: (B:) hla class II histocompatibility antigen, dr-1 beta chain

SCOP Domain Sequences for d1jwsb1:

Sequence, based on SEQRES records:

>d1jwsb1 b.1.1.2 (B:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvepkvtvypsktqplqhhnllvcsvsgfypgsievrwfrngqeekagvvstgliqngd
wtfqtlvmletvprsgevytcqvehpsvtspltvewra

Sequence, based on observed residues (ATOM records):

>d1jwsb1 b.1.1.2 (B:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvepkvtvypsktqhhnllvcsvsgfypgsievrwfrngqeekagvvstgliqngdwtf
qtlvmletvprsgevytcqvehpsvtspltvewra

Timeline for d1jwsb1:

• d1jwsb1 first appeared in SCOP 1.65
  
• d1jwsb1 appears in SCOP 1.71
  
• d1jwsb1 appears in SCOP 1.75
  
• d1jwsb1 appears in the current release, SCOPe 2.08