SCOP 1.75: Domain d1jwmb1: 1jwm B:93-190

Lineage for d1jwmb1 (1jwm B:93-190)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (28 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (4 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (23 proteins)

6. Protein Class II MHC beta chain, C-terminal domain [88625] (6 species)

7. Species Human (Homo sapiens), HLA-DR group [TaxId:9606] [88628] (39 PDB entries)
   Uniprot P04229 30-219
   probably orthologous to the mouse I-E group

8. Domain d1jwmb1: 1jwm B:93-190 [84238]
   Other proteins in same PDB: d1jwma1, d1jwma2, d1jwmb2, d1jwmd1, d1jwmd2

Details for d1jwmb1

PDB Entry: 1jwm, 2.7 Å

PDB Description: Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3

PDB Compounds: (B:) hla class II histocompatibility antigen, dr-1 beta chain

SCOP Domain Sequences for d1jwmb1:

Sequence, based on SEQRES records:

>d1jwmb1 b.1.1.2 (B:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvepkvtvypsktqplqhhnllvcsvsgfypgsievrwfrngqeekagvvstgliqngd
wtfqtlvmletvprsgevytcqvehpsvtspltvewra

Sequence, based on observed residues (ATOM records):

>d1jwmb1 b.1.1.2 (B:93-190) Class II MHC beta chain, C-terminal domain {Human (Homo sapiens), HLA-DR group [TaxId: 9606]}
rrvepkvtvypsktqhhnllvcsvsgfypgsievrwfrngqeekagvvstgliqngdwtf
qtlvmletvprsgevytcqvehpsvtspltvewra

Timeline for d1jwmb1:

• d1jwmb1 first appeared in SCOP 1.65
  
• d1jwmb1 appears in SCOP 1.73
  
• d1jwmb1 appears in SCOPe 2.01
  
• d1jwmb1 appears in the current release, SCOPe 2.08