Lineage for d1h06a_ (1h06 A:)

  1. Root: SCOP 1.65
  2. 323018Class d: Alpha and beta proteins (a+b) [53931] (234 folds)
  3. 334933Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 334934Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (6 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 334971Family d.144.1.7: Protein kinases, catalytic subunit [88854] (41 proteins)
    members organised in the groups and subfamiles specified by the comments
  6. 335059Protein Cyclin-dependent PK, CDK2 [88855] (1 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 335060Species Human (Homo sapiens) [TaxId:9606] [88856] (53 PDB entries)
  8. 335106Domain d1h06a_: 1h06 A: [83417]
    complexed with 3fp, 3fq, ace

Details for d1h06a_

PDB Entry: 1h06 (more details), 2.31 Å

PDB Description: cdk2 in complex with a disubstituted 4, 6-bis anilino pyrimidine cdk4 inhibitor

SCOP Domain Sequences for d1h06a_:

Sequence, based on SEQRES records: (download)

>d1h06a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

Sequence, based on observed residues (ATOM records): (download)

>d1h06a_ d.144.1.7 (A:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens)}
menfqkvekigegtygvvykarnkltgevvalkkirltaireisllkelnhpnivklldv
ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
pqnllintegaikladfglarvvtlwyrapeillgckyystavdiwslgcifaemvtrra
lfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrs
llsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOP Domain Coordinates for d1h06a_:

Click to download the PDB-style file with coordinates for d1h06a_.
(The format of our PDB-style files is described here.)

Timeline for d1h06a_:

  • d1h06a_ is new in SCOP 1.65
  • d1h06a_ became obsolete in SCOP 1.67